EFFECTS OF INTERFERON THERAPY UPON IMMUNE MARKER PROFILE AND ENZYMATIC ACTIVITY IN PERIPHERAL BLOOD LYMPHOCYTES OF PATIENTS WITH RENAL CANCER
https://doi.org/10.15789/1563-0625-2014-3-281-288
Abstract
We have observed forty-four patients with metastatic renal cancer before and after interferon therapy. Immune markers of of peripheral blood lymphocytes were determined by flow cytometry. Activity of NAD (P)-dependent dehydrogenase in blood lymphocytes was studied by means of bioluminescence technique. Changes of immune marker profiles and enzymatic activities of peripheral blood lymphocytes were found in patients with renal cancer after a course of interferon therapy.
About the Authors
L. M. Kurtasova
Krasnoyarsk State V.F. Voyno-Yasenetsky Medical University, Ministry of Health Care of Russian Federation, Krasnoyarsk
Russian Federation
Russian Federation
PhD, MD (Medicine), Professor,Clinical Immunology Department, Krasnoyarsk State V.F. Voyno-Yasenetsky Medical University, Ministry of Health Care of Russian Federation
R. A. Zukov
Krasnoyarsk State V.F. Voyno-Yasenetsky Medical University, Ministry of Health Care of Russian Federation, Krasnoyarsk
Russian Federation
Russian Federation
PhD (Medicine), Assistant Professor, Department of Oncology and Radiation Therapy, Krasnoyarsk State V.F. Voyno-Yasenetsky Medical University, Ministry of Health Care of Russian Federation
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Review
For citations:
Kurtasova L.M., Zukov R.A. EFFECTS OF INTERFERON THERAPY UPON IMMUNE MARKER PROFILE AND ENZYMATIC ACTIVITY IN PERIPHERAL BLOOD LYMPHOCYTES OF PATIENTS WITH RENAL CANCER. Medical Immunology (Russia). 2014;16(3):281-288. (In Russ.) https://doi.org/10.15789/1563-0625-2014-3-281-288
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