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ROLE OF ENDOTHELIAL CELLS IN REGULATION OF APOPTOSIS OF HIV-1 INFECTED CD4+ LYMPHOCYTES

https://doi.org/10.15789/1563-0625-2006-4-523-530

Abstract

Abstract. Vascular endothelial cells (VECs) are able to induce HIV1 replication in СD4+ Tcells, thus determining their resistance for apoptosis. The revealed facts are specific to EC/Tcell culture and are stipulated by the cellcell interactions between the VECs and HIV1 producing cells, thus being a consequence of activation of ‘productively infected’ T cells.

About the Authors

S. V. Boichuk
Казанский государственный медицинский университет; Республиканский центр по профилактике и борьбе со СПИД и ИЗ МЗ РТ
Russian Federation


I. G. Mustafin
Казанский государственный медицинский университет; Республиканский центр по профилактике и борьбе со СПИД и ИЗ МЗ РТ
Russian Federation


M. V. Makarova
Казанский государственный медицинский университет; Республиканский центр по профилактике и борьбе со СПИД и ИЗ МЗ РТ
Russian Federation


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Review

For citations:


Boichuk S.V., Mustafin I.G., Makarova M.V. ROLE OF ENDOTHELIAL CELLS IN REGULATION OF APOPTOSIS OF HIV-1 INFECTED CD4+ LYMPHOCYTES. Medical Immunology (Russia). 2006;8(4):523-530. (In Russ.) https://doi.org/10.15789/1563-0625-2006-4-523-530

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