ФУНДАМЕНТАЛЬНАЯ ИММУНОБИОЛОГИЯ ПРОВОСПАЛИТЕЛЬНЫХ ЦИТОКИНОВ И MIF
https://doi.org/10.15789/1563-0625-2006-1-5-22
Аннотация
Резюме. Сравнение цитокинов и MIF по основным общебиологическим свойствам показывает наличие, как сходства, так и существенных различий. Особенностями MIF являются уникальность его структуры, повсеместная распространенность в органах и тканях организма, исключительно широкое разнообразие функций (провоспалительный цитокин, фермент, гормон), способность индуцироваться глюкокортикои дами и оказывать контррегулирующее действие на их иммуносупрессивные эффекты. MIF находится в преформированном состоянии в лимфоцитах, макрофагах и клетках эндотелия. Он выделяется этими клетками и функционирует как фактор мобилизации защитной системы уже в первые минуты чужеродного воздействия. MIF проявляет свойства суперлиганда, связываясь со множеством биологически важных молекул, Этот фактор осуществляет функции, важные для активации клетки, ее размножения и гибели, используя разнообразные внутриклеточные сигнальные пути. В эволюции гомологи MIF обнаруживают уже у растений и бактерий, то есть до появления адоптивной и врожденной иммунной системы. В онтогенезе MIF появляется уже на стадии первых клеточных делений. Широта функций MIF многообразие его лига дных связей, разнообразие путей реализации функций, повсеместное распространения в организме, раннее появление в онтогенезе и филогенезе, а также в ходе защитной реакции клетки и организма в целом – все эти факторы вместе взятые позволяют позиционировать MIF как особый тип цитокина – эоцитокин (от греческого эо – ранний). Предполагается, что MIF может функционировать как ключевой фактор «естественной устойчивости» клетки и организма.
Об авторах
А. П. Суслов
ГУ НИИЭМ им.Н.Ф.Гамалеи РАМН, Москва
Россия
Россия
лаборатория эффекторов и медиаторов воспаления
123098, ул.Гамалеи, д.18. Тел.: (495)193‑61‑31, факс (495) 193‑43‑50
М. В. Коноплева
ГУ НИИЭМ им.Н.Ф.Гамалеи РАМН, Москва
Россия
Россия
лаборатория эффекторов и медиаторов воспаления
О. Ю. Третьяков
ГУ НИИЭМ им.Н.Ф.Гамалеи РАМН, Москва
Россия
Россия
лаборатория эффекторов и медиаторов воспаления
Список литературы
1. Abe R., Peng T., Sailors J., Bucala R., Metz C.N. Regulation of the CTL response by macrophage migration inhibitory factor // J. Immunol.-2001.-Vol.166, №2.-P.747-753.
2. Abe R., Shimizu T., Ohkawara A., Nishihira J. Enhancement of macrophage migration inhibitory factor (MIF) expression in injured epidermis and cultured fibroblasts // Biochim. Biophys. Acta -2000.-Vol.1500, №1.-P.1-9.
3. Akoum A., Metz C.N., Morin M. Marked increase in macrophage migration inhibitory factor synthesis and secretion in human endometrial cells in response to human chorionic gonadotropin hormone // J. Clin. Endocrinol. Metab.-2005.-Vol.90, №5.-P.2904-2910.
4. Alourfi Z., Donn R., Stevens A., Berry A., McMaster A., Ray D. Glucocortikoids suppress macrophage migration inhibitory factor (MIF) expression in a cell-type-specific manner // J. Mol. Endocrinol.-2005.- V.34. - № 2.- P. 583-595.
5. Amin M.A., Volpert O.V., Woods J.M., Kumar P., Harlow L.A., Koch A.E. Migration inhibitory factor mediates angiogenesis via mitogen-activated protein kinase and phosphatidylinositol kinase // Circ. Res.- 2003.-Vol.93, №4.-P.321-329.
6. Angeli A., Masera R.G., Sartori M.L., Fortunati N., Racca S., Dovio A., Staurenghi A., Frairia R. Modulation by cytokines of glucocorticoid action // Ann. N. Y. Acad. Sci.-1999.-Vol.876.-P.210-220.
7. Apte R.S., Sinha D., Mayhew E., Wistow G.J., Niederkorn J.Y. Cutting edge: role of macrophage mi- gration inhibitory factor in inhibiting NK cell activity and preserving immune privilege // J. Immunol.-1998.- Vol.160, №12.-P.5693-5696.
8. Arcuri F., Cintorino M., Vatti R., Carducci A., Liberatori S., Paulesu L. Expression of macrophage migration inhibitory factor transcript and protein by first-trimester human trophoblasts // Biol. Reprod.- 1999.-Vol.60, №6.-P.1299-1303.
9. Bacher M., Metz C.N., Calandra T., Mayer K., Chesney J., Lohoff M., Gemsa D., Donnelly T., Bucala R. An essential regulatory role for macrophage migration inhibitory factor in T-cell activation // PNAS- 1996.-Vol.93.-P.7849-7854.
10. Bacher M., Schrader J., Thompson N., Kuschela K., Gemsa D., Waeber G., Schlegel J. Up-regulation of macrophage migration inhibitory factor gene and protein expression in glial tumor cells during hypoxic and hypoglycemic stress indicates a critical role for angiogenesis in glioblastoma multiforme // Am. J. Pathol.- 2003.-Vol.162, №1-P.11-17.
11. Baumann R., Casaulta C., Simon D., Conus S., Yousefi S., Simon H.U. Macrophage migration inhibitory factor delays apoptosis in neutrophils by inhibitng the mitochondria-dependent death pathway // FASEB J.-2003.-Vol.17, №15.-P.2221-2230.
12. Bendrat K., Al-Abed Y., Callaway D.J., Peng T., Calandra T., Metz C.N., Bucala R. Biochemical and mutational investigations of the enzymatic activity of macrophage migration inhibitory factor // Biochemistry.-1997.-Vol.36, №49.-P.15356-15362.
13. Benigni F., Atsumi T., Calandra T., Metz C., Echtenacher B., Peng T., Bucala R. The proinflammatory mediator macrophage migration inhibitory factor induces glucose catabolism in muscle // J. Clin. Invest.- 2000.-Vol.106, №10.-P.1291-300.
14. Blocki F.A., Ellis L.B., Wackett L.P. MIF protein are theta-class glutathione S-transferase homologs // Protein Sci.-1993.-Vol.2, №12.-P.2095-2102.
15. Blocki F.A., Schlievert P.M., Wackett L.P. Rat liver protein linking chemical and immunological detoxification systems // Nature-1992.-Vol.360, №6401.- P.269-270.
16. Bloom B.R., Bennet B. Mechanism of reaction in vitro associated with delayed-type hypersensitivity // Science-1966.-Vol.153.-P.80-82.
17. Bornstein S.R., Chrousos G.P. Adrenocorticotropin (ACTH)- and non-ACTH-mediated regulation of the adrenal cortex: neural and immune inputs // J. Clin. Endocrinol. Metab.-1999.-Vol.84, №5.-P.1729-1736.
18. Brown F.G., Nikolic-Paterson D.J., Chadban S.J., Dowling J., Jose M., Metz C.N., Bucala R., Atkins R.C. Urine macrophage migration inhibitory factor concentrations as a diagnostic tool in human renal allograft rejection // Transplantation-2001.-Vol.71, №12.- P.1777-1783.
19. Bucala R. Neuroimmunomodulation by macrophage migration inhibitory factor (MIF) // Ann. N.Y. Acad. Sci.-1998.-Vol.840, №1.-P.74-82.
20. Burger-Kentischer A., Finkelmeier D., Thiele M., Schmucker J., Geiger G., Tovar G.E., Bernhagen J. Binding of JAB1/CSN5 to MIF is mediated by the MPN domain but is independent of the JAMM motif // FEBS Lett.-2005.-Vol.579, №7.-P.1693-1701.
21. Calandra T., Bernhagen J., Metz C.N., Spiege L.A., Bacher M., Donnelly T., Cerami A., Bucala R. MIF as a glucocorticoid-induced modulator of cytokine production // Nature–1995.-Vol.377.-P.68-71.
22. Calandra T., Roger T. Macrophage migration inhibitory factor: a regulator of innate immunity // Nat. Rev. Immunol.-2003.-Vol.3, №10.-P.791-800.
23. Chagnon F., Metz C.N., Bucala R., Lesur O. Endotoxininduced myocardial dysfunction: effects of macrophage migration inhibitory factor neutralization // Circ. Res.-2005.-Vol.96, №10.-P.1095-1102.
24. Chaput M., Claes V., Portetelle D., Cludts I., Cravador A., Burny A., Gras H., Tartar A. The neurotrophic factor neuroleukin is 90% homologous with phosphohexose isomerase // Nature-1988.-Vol.332, №6163.-P.454-455.
25. Chen Z., Sakuma M., Zago A.C., Zhang X., Shi C., Leng L., Mizue Y., Bucala R., Simon D.I. Evidence for a role of macrophage migration inhibitory factor in vascular disease // Arterioscler. Thromb. Vasc. Biol.- 2004.-Vol.24.-P.709-714.
26. Chesney J., Metz C., Bacher M., Peng T., Meinhardt A., Bucala R. An essential role for macrophage migration inhibitory factor (MIF) in angiogenesis and growth of a murine lymphoma // Mol. Med.-1999.- Vol.5, №3.-P.181-191.
27. Collette Y., Gilles A., Pontarotti P., Olive D. A co-evolution perspective of the TNFSF and TNFRSF families in the immune system // Trends Immunol.- 2003.-Vol. 24, №7.-P.387-394.
28. Cordon-Cardo C., Prives C. At the crossroads of inflammation and tumorigenesis // J. Exp. Med.- 1999.-Vol.190, №10.-P.1367-1370.
29. Cunha F.Q., Weiser W.Y., David J.R., Moss D.W., Moncada S., Liew F.Y. Recombinant migration inhibitory factor induces nitric oxide synthase in murine macrophages // J. Immunol.-1993.-Vol.150, №5.- P.1908-1912.
30. Daun J.M., Cannon J.G. Macrophage migration inhibitory factor antagonizes hydrocortisone-induced increases in cytosolic IκBα // Am. J. Physiol. Regul. Integr. Comp. Physiol.-2000.-Vol.279, №3.-P.R1043- R1049.
31. David J.R. Delayed hypersensitivity in vitro. The modulation by cell-free substances formed by lymphoid cell-antigen interaction // PNAS – 1966.- Vol.56.- P.72-77.
32. Denkinger C.M., Metz C., Fingerle-Rowson G., Denkinger M.D., Forsthuber T. Macrophage migration inhibitory factor and its role in autoimmune diseases // Arch. Immunol. Ther. Exp.-2004.-Vol.52, №6.-P.389- 400.
33. Donn R.P., Ray D.W. Macrophage migration inhibitory factor: molecular, cellular and genetic aspects of a key neuroendocrine molecule // J. Endocrinol.- 2004.-Vol.182.-P.1-9.
34. Donnelly S.C., Haslett C., Reid P.T., Grant I.S., Wallace W.A., Metz C.N., Bruce L.J.,Bucala R. Regulatory role for macrophage migration inhibitory factor in acute respiratory distress syndrome // Nat. Med.- 1997.-Vol.3, №3.-P.320-323.
35. Ealick S.E., Cook W.J., Vijay-Kumar S., Carson M., Nagabhushan T.L., Trotta P.P., Bugg C.E. Three-di- mensional structure of recombinant human interferon- gamma // Science-1991.-Vol.252, №5006.-P.698-702.
36. Eickhoff R., Baldauf C., Koyro H.W., Wennemuth G., Suga Y., Seitz J., Henkel R., Meinhardt A. Influence of macrophage migration inhibitory factor (MIF) on the zinc content and redox state of protein bound sulphydryl groups in rat sperm: indications for a new role of MIF in sperm maturation // Mol. Hum. Reprod.-2004.-Vol.10, №8.-P.605-611.
37. Esumi N., Budarf M., Ciccarelli L., Sellinger B., Kozak C.A., Wistow G. Conserved gene structure and genomic linkage for D-dopachrome tautomerase (DDT) and MIF // Mamm. Genome.-1998.-Vol.9, №9.-P.753-757.
38. Fingerle-Rowson G., Koch P., Bikoff R., Lin X., Metz C.N., Dhabhar F.S., Meinhardt A.,Bucala R. Regulation of macrophage migration inhibitory factor expression by glucocorticoids in vivo // Am. J. Pathol.- 2003.-Vol.162, №1.-P.47-56.
39. Fingerle-Rowson G., Petrenko O., Metz C.N., Forsthuber T.G., Mitchell R., Huss R., Moll U., Muller W., Bucala R. The p53-dependent effects of macrophage migration inhibitory factor revealed by gene targeting // PNAS-2003.-Vol.100, №16.-P.9354-9359.
40. Flieger O., Engling A., Bucala R., Lue H., Nickel W., Bernhagen J. Regulated secretion of macrophage migration inhibitory factor is mediated by a non-classical pathway involving an ABC transporter // FEBS Lett.-2003.-Vol.551, №1-3.-P.78-86.
41. Fukuzawa J., Nishihira J., Hasebe N., Haneda T., Osaki J., Saito T., Nomura T., Fujino T., Wakamiya N., Kikuchi K. Contribution of macrophage migration inhibitory factor to extracellular signal-regulated kinase activation by oxidative stress in cardiomuocytes // J. Biol. Chem.-2002.-Vol.277, №28.-P.24889-24895.
42. Galat A., Riviere S., Bouet F., Menez A. A diversified family of 12-kDa proteins with a high amino acid sequence similarity to macrophage migration-inhibitory factor (MIF) // Eur. J. Biochem.-1994.-Vol.224, №2.- P.417-421.
43. Garai J., Adlercreutz H. Estrogen-inducible uterine flavonoid binding sites: is it time to reconsider? // J. Steroid. Biochem Mol. Biol.-2004.-Vol.88, №4-5.-P.377-381.
44. Goetz F.W., Planas J.V., MacKenzie S. Tumor necrosis factors // Dev. Comp. Immunol.-2004.-Vol.28, №5.-P.487-497.
45. Herriott M.J., Jiang H., Stewart C.A., Fast D.J., Leu R.W. Mechanistic differences between migration inhibitory factor (MIF) and IFN-γ for macrophage activation // J. Immunol.-1993.-Vol.150, ¹10.-P.4524-4531.
46. Higgins T.J., Liu D.Y., Remold H.G., David J.R. Further characterization of the putative glycolipid receptor for MIF: role of fucose associated with an acidic glycolipid // Biochem. Biophys. Res. Commun.-1980.- Vol.93, №4.-P.1259-1265.
47. Hoogewerf A.J., Leone J.W., Reardon I.M., Howe W.J., Asa D., Heinrikson R.L., Ledbetter S.R. CXC chemokines connective tissue activating peptide-III and neutrophil activating peptide-2 are heparin/heparan sulfate-degrading enzymes // J. Biol. Chem.-1995.- Vol.270, №7.-P.3268-3277.
48. Hudson J.D., Shoaibi M.A., Maestro R., Carnero A., Hannon G.J., Beach D.H. A proinflammatory cytokine inhibits p53 tumor suppressor activity // J. Exp. Med.-1999.-Vol.190, №10.-P.1375-1382.
49. Jaworski D.C., Jasinskas A., Metz C.N., Bucala R., Barbour A.G. Identification and characterization of a homologue of the pro-inflammatory cytokine Macrophage Migration Inhibitory Factor in the tick, Amblyomma americanum // Insect. Mol. Biol.-2001.- Vol.10, №4.-P.323-331.
50. Josephson K., DiGiacomo R., Indelicato S.R., Iyo A.H., Nagabhushan T.L., Parker M.H., Walter M.R. Design and analysis of an engineered human interleukin-10 monomer // J. Biol. Chem.-2000.-Vol.275, №18.-P.13552-13557.
51. Jung H., Kim T., Chae H.Z., Kim K.T., Ha H. Regulation of macrophage migration inhibitory factor and thiolpecific antioxidant protein PAG by direct interaction // J. Biol. Chem.-2001.-Vol.276, №18.- P.15504-15510.
52. Juttner S., Bernhagen J., Metz C.N., Rollinghoff M., Bucala R., Gessner A. Migration inhibitory factor induces killing of Leishmania major by macrophages: dependence on reactive nitrogen intermediates and endogenous TNF-α // J. Immunol.-1998.-Vol.161.-P.2383-2390.
53. Kaiser P., Rothwell L., Avery S., Balu S. Evolution of the interleukins // Dev. Comp. Immunol.-2004.- Vol.28, №5.-P.375-394.
54. Kameoka J., Tanaka T., Nojima Y., Schlossman S.F., Morimoto C. Direct association of adenosine deaminase with a T cell activation antigen, CD26 // Science-1993.-Vol.261, №5120.-P.466-469.
55. Kerkhoff c., Klempt M., Sorg. Novel insights into structure and function of MRP8 (S100A8) and MRP14 (S100A9). // Biochim. Biophys. Acta.-1998.-V.1448.- No2.-P.200-211.
56. Kitaichi N., Kotake S., Mizue Y., Sasamoto Y., Goda C., Iwabuchi K., Onoe K., Matsuda H., Nishihira J. High-dose corticosteroid administration induces in- crease of serum macrophage migration inhibitory factor in patients with Vogt-Koyanagi-Harada’s disease // Microbiol. Immunol.-2000.-Vol.44, №12.-P.1075- 1077.
57. Kleemann R., Grell M., Mischke R., Zimmermann G., Bernhagen J. Receptor binding and cellular uptake studies of macrophage migration inhibitory factor (MIF): use of biologically active labeled MIF derivatives // J. Interferon. Cytokine Res.-2002.-Vol.22, №3.-P.351-363.
58. Kleemann R., Hausser A., Geiger G., Mischke R., Burger-Kentischer A., Flieger O., Johannes F.J., Roger T., Calandra T., Kapurniotu A., Grell M., Finkelmeier D., Brunner H., Bernhagen J. Intracellular action of the cytokine MIF to modulate AP-1 activity and the cell cycle through Jab1 // Nature-2000.- Vol.408, №6809.-P.211-216.
59. Kleemann R., Kapurniotu A., Frank R.W., Gessner A., Mischke R., Flieger O., Juttner S., Brunner H., Bernhagen J. Disulfide analysis reveals a role for macrophage migration inhibitory factor(MIF) as thiol-protein oxidoreductase // J. Mol. Biol.-1998.-Vol.280, №1.-P.85-102.
60. Kleemann R., Kapurniotu A., Mischke R., Held J., Bernhagen J. Characterization of catalytic centre mutants of macrophage migration inhibitory factor (MIF) and comparison to Cys81Ser MIF // Eur. J. Biochem.-1999.-Vol.261, №3.-P.753-766.
61. Kleemann R., Mischke R., Kapurniotu A., Brunner H., Bernhagen J. Specific reduction of insulin disulfides by macrophage migration inhibitory factor (MIF) with glutathione and dihydrolipoamide: potential role in cellular redox processes // FEBS Lett.-1998.- Vol.430, №3.-P.191-196.
62. Kultz D. Evolution of the cellular stress proteome: from monophyletic origin to ubiquitous function // J. Exp. Biol.-2003.-Vol.206, Pt.18.-P.3119-24.
63. Kuriyama T., Fujinaga M., Koda T., Nishihira J. Cloning of the mouse gene for D-dopachrome tautomerase // Biochim. Biophys. Acta.-1998.-Vol.1388, №2.-P.506-512.
64. Laing K.J., Secombes C.J. Chemokines // Dev. Comp. Immunol.-2004.-Vol.28, №5.-P.443-460.
65. Lan H.Y., Bacher M., Yang N., Mu W., Nikolic-Paterson D.J., Metz C., Meinhardt A., Bucala R., Atkins R.C. The pathogenic role of macrophage migration inhibitory factor in immunologically induced kidney disease in the rat // J. Exp. Med.-1997.-Vol.185, №8.-P.1455-1465.
66. Lanahan A., Williams J.B., Sanders L.K., Nathans D. Growth factor-induced delayed early response genes // Mol. Cell. Biol.-1992.-Vol.12, №9.-P.3919-3929.
67. Lechmann L., Weber S., Fuchs D., Klaschik S., Shewe J., Book M., Hoeft A., Stuber F. // Free Radic. Biol. Med.-2005.-V. 38.-№9.-P.117—1179.
68. Leiva M.C., Lyttle C.R. Leukocyte chemotactic activity of FKBP and inhibition by FK506 // Biochem. Biophys. Res. Commun.-1992.-Vol.186, №2.-P.1178- 1183.
69. Leng L., Metz C.N., Fang Y., Xu J., Donnelly S., Baugh J., Delohery T., Chen Y., Mitchell R.A., Bucala R. MIF signal transduction initiated by binding to CD74 // J. Exp. Med.-2003.-Vol.197, №11.-P.1467-1476.
70. Leonard W.J. Cytokines and immunodeficiency disease // Nature Rew.-2001.-Vol.1.-P.200-208.
71. Leung J.C., Chan L.Y., Tsang A.W., Liu E.W., Lam M.F., Tang S.C., Lai K.N. Anti-macrophage migration inhibitory factor reduces transforming growth- factor-beta 1 expression in experimental IgA nephropathy // Nephrol. Dial. Transplant.-2004.-Vol.19, №8.- P.1976-1985.
72. Li Z., Ren Y., Wu Q.C., Lin S.X., Liang Y.J., Liang H.Z. Macrophage migration inhibitory factor enhances neoplastic cell invasion by inducing the expression of matrix metalloproteinase 9 and interleukin-8 in nasopharyngeal carcinoma cell lines // Chin. Med. J. (Engl).-2004.-Vol.117, №1.-P.107-114.
73. Lin S.G., Yu X.Y., Chen Y.X., Huang X.R., Metz C., Bucala R., Lau C.P., Lan H.Y. De novo expression of macrophage migration inhibitory factor in atherogenesis in rabbits // Circ. Res.-2000.-Vol.87, №12.- P.1202-1208.
74. Lolis E., Bucala R. Macrophage migration in- hibitory factor // Expert. Opin. Ther. Targets.-2003.- Vol.7, №2.-P.153-164.
75. Lubetsky J.B., Dios A., Han J., Aljabari B., Ruzsicska B., Mitchell R., Lolis E., Al-Abed Y. The tautomerase active site of macrophage migration inhibitory factor is a potential target for discovery of novel anti- inflammatory agents // J. Biol. Chem.-2002.-Vol.277, №28.-24976-24982.
76. Makita H., Nishimura M., Miyamoto K., Nakano T., Tanino Y., Hirokawa J., Nishihira J., Kawakami Y. Effect of anti-macrophage migration inhibitory factor antibody on lipopolysaccharide-induced pulmonary neutrophil accumulation // Am. J. Respir. Crit. Care. Med.-1998.-Vol.158, №2.-P.573-579.
77. Marson AL, Tarr DE, Scott AL. Macrophage migration inhibitory factor (mif) transcription is significantly elevated in Caenorhabditis elegans dauer larvae // Gene-2001.-Vol.278, №1-2.-P.53-62.
78. Matsunaga J., Sinha D., Pannell L., Santis C., Solano F., Wistow G.J., Hearing V.J. Enzyme activity of macrophage migration inhibitory factor toward oxidized catecholamines // J. Biol. Chem.-1999.-Vol.274, №6.-P.3268-3271.
79. Messmer U.K., Brune B. Nitric oxide-induced apoptosis: p53-dependent and p53-independent signaling pathways // Biochem. J.-1996.-Vol.319, Pt.1. - P.299-305.
80. Mikayama T., Nakano T., Gomi H., Nakagawa Y., Liu Y.C., Sato M., Iwamatsu A., Ishii Y., Weiser W.Y., Ishizaka K. Molecular cloning and functional expression of a cDNA encoding glycosylation-inhibiting factor // PNAS-1993.-Vol.90, №21.-P.10056- 10060.
81. Mitchell R.A., Metz C.N., Peng T., Bucala R. Sustained mitogen-activated protein kinase (MAPK) and cytoplasmic phospholipase A2 activation by macrophage migration inhibitory factor (MIF). Regulatory role in cell proliferation and glucocorticoid action // J. Biol. Chem.-1999.-Vol.274, №25.-P.18100-18106.
82. Nguyen M.T., Beck J., Lue H., Funfzig H., Kleemann R., Koolwijk P., Kapurniotu A.,Bernhagen J. A 16-residue peptide fragment of macrophage migration inhibitory factor, MIF-(50-65), exhibits redox activity and has MIF-like biological functions // J. Biol. Chem.-2003.-Vol.278, №36.-P.33654-33671.
83. Nguyen M.T., Lue H., Kleemann R., Thiele M., Tolle G., Finkelmeier D., Wagner E., Braun A., Bernhagen J. The cytokine macrophage migration inhibitory factor reduces pro-oxidative stress-induced apoptosis // J. Immunol.-2003.-Vol.170, №6.-P.3337-3347.
84. Onodera S., Nishihira J., Iwabuchi K., Koyama Y., Yoshida K., Tanaka S., Minami A. Macrophage migration inhibitory factor up-regulates matrix metalloproteinase-9 and -13 in rat osteoblasts. Relevance to intracellular signaling pathways // J. Biol. Chem. - 2002.-Vol.277, №10.-P.7865-7874.
85. Onodera S., Suzuki K., Matsuno T., Kaneda K., Takagi M., Nishihira J. Macrophage migration inhibitory factor induces phagocytosis of foreign particles by macrophages in autocrine and paracrine fashion // Immunology-1997.-Vol.92.-P.131-137.
86. Ottaviani E., Malagoli D., Franchini A. Invertebrate humoral factors: cytokines as mediators of cell survival // Prog. Mol/ Subcell. Biol. – 2004.-Vol.34.-P.1-25.
87. Papa S., Zazzeroni F., Pham C.G., Bubici C., Franzoso G. Linking JNK signaling to NF-κB: a key to survival // J. Cell. Sci.-2004.-Vol.117, №Pt22.-P.5197- 5208.
88. Pennock J.L., Wipasa J., Gordge M.P., Meyer D.J. Interaction of macrophage-migration-inhibitory factor with haematin // Biochem. J.-1998.-Vol.331, Pt.3.-P.905-908.
89. Pestka S., Krause C.D., Sarkar D., Walter M.R., Shi Y., Fisher P.B. Interleukin-10 and related cytokines and receptors // Annu. Rev. Immunol.-2004.- Vol.22.-P.929-979.
90. Petrenko O., Fingerle-Rowson G., Peng T., Mitchell R.A., Metz C.N. Macrophage migration inhibitory factor deficiency is associated with altered cell growth and reduced susceptibility to Rasmediated transformation // J. Biol. Chem.-2003.-Vol.278, №13.- P.11078-11085.
91. Petrovsky N., Bucala R. Macrophage migration inhibitory factor (MIF). A critical neurohumoral mediator // Ann. N. Y. Acad. Sci.-2000.-Vol.917.-P.665- 671.
92. Potolicchio I., Santambrogio L., Strominger J.L. Molecular interaction and enzymatic activity of macrophage migration inhibitory factor with immunorelevant peptides // J. Biol. Chem.-2003.-Vol.278, №33. - P.30889-30895.
93. Pozzi L.M., W.Y. Weiser. Recombinant human macrophage migration inhibitory factor activates human monocyte derived macrophages to kill tumor tar- gets // FASEB J.-1991.-Vol.5.-P.A4184.
94. Ren Y., Tsui H.T., Poon R.T., Ng I.O., Li Z., Chen Y., Jiang G., Lau C., Yu W.C., Bacher M., Fan S.T. Macrophage migration inhibitory factor: roles in regulation tumor cell migration and expression of angiogenic factors in hepatocellular carcinoma // Cancer-2003.- Vol.107, №1.-P.22-29.
95. Rosengren E., Aman P., Thelin S., Hansson C., Ahlfors S., Bjork P., Jacobsson L., Rorsman H. The macrophage migration inhibitory factor MIF is a phenylpyruvate tautomerase // FEBS Lett.-1997.-Vol.417, №1.-P.85-88.
96. Rosengren E, Bucala R, Aman P, Jacobsson L, Odh G, Metz CN, Rorsman H. The immunoregulatory mediator macrophage migration inhibitory factor (MIF) catalyzes a tautomerization reaction // Mol. Med.-1996.-Vol.2, №1.-P.143-149.
97. Sakai M., Nishihira J., Hibiya Y., Koyama Y., Nishi S. Glutathione binding rat liver 13k protein is the homologue of the macrophage migration inhibitory factor // Biochem. Mol. Biol. Int.-1994.-Vol.33, №3.- P.439-446.
98. Sampey A.V., Hall P.H., Mitchell R.A., Metz C.N., Morand E.F. Regulation of synoviocyte phospholipase A2 and cyclooxygenase 2 by macrophage migration inhibitory factor // Arthritis Rheum.-2001.- Vol.44, №6.-P.1273-1280.
99. Santos L., Hall P., Metz C., Bucala R., Morand E.F. Role of macrophage migration inhibitory factor (MIF) in murine antigen-induced arthritis: interaction with glucocorticoids // Clin. Exp. Immunol.-2001.- Vol.123, №2.-P.309-314.
100. Santos L.L., Lacey D., Yang Y., Leech M., Mo- rand E.F. Activation of synovial cell p38 MAP kinase by macrophage migration inhibitory factor // J. Rheumatol.-2004.-Vol.31, №6.-P.1038-1043.
101. Satoskari A.R., Bozza M., Rodriguez Sosa M., Lin G., David J.R. Migration-inhibitory factor gene- deficient mice are susceptible to cutaneous Leishmania major infection // Infect. Immun.-2001.-Vol.69, №2. - P.906-911.
102. Senda T., Shimazu T., Matsuda S., Kawano G., Shimizu H., Nakamura K.T., Mitsui Y. Threedimensional crystal structure of recombinant murine interferon beta // EMBO J.-1992.-Vol.11, №9.-P.3193- 3201.
103. Shen L., Hu J., Lu H., Wu M., Qin W., Wan D., Li Y.Y., Gu J. The apoptosis-associated protein BNIPL interacts with two cell proliferation-related proteins, MIF and GFER // FEBS Lett.-2003.-Vol.540, №1-3.- P.86-90.
104. Sherry B., Yarlett N., Strupp A., Cerami A. Identification of cyclophilin as a proinflammatory secretory product of lipopolysaccharide-activated macrophages // PNAS-1992.-Vol.89, №8.-P.3511-3515.
105. Shimizu T., Nishihira J., Watanabe H., Abe R., Ishibashi T., Shimizu H. Cetirizine, an H1-receptor antagonist, suppresses the expression of macrophage migration inhibitory factor: its potential anti-inflammatory action // Clin. Exp. Allergy.-2004.-Vol.34, №1.- P.103-109.
106. Shimizu T., Nishihira J., Watanabe H., Abe R., Honda A., Ishibashi T., Shimizu H. Macrophage migration inhibitory factor is induced by thrombin and factor Xa in endothelial cells // J. Biol. Chem.-2004.- Vol.279, №14.-P.13729-13737.
107. Stavitsky A.B., Xianli J. In vitro and in vivo regulation by macrophage migration inhibitory factor (MIF) of expression of MHC-II, costimulatory, adhesion, receptor, and cytokine molecules. // Cell Immunol.-2002.-Vol.217, №1-2.-P.95-104.
108. Sugimoto H, Suzuki M, Nakagawa A, Tanaka I, Nishihira J. Crystal structure of macrophage migration inhibitory factor from human lymphocyte at 2.1 A resolution // FEBS Lett.-1996.-Vol.389, №2.-P.145- 148.
109. Sugimoto H., Taniguchi M., Nakagawa A., Tanaka I., Suzuki M., Nishihira J. Crystal structure of human D-dopachrome tautomerase, a homologue of macrophage migration inhibitory factor, at 1.54 A resolution // Biochemistry-1999.-Vol.38? №11.-P.3268- 3279.
110. Sun B., Nishihira J., Suzuki M.,Fukushima N., Ishibashi T., Kondo M., Sato Y., Todo S. Induction of macrophage migration inhibitory factor by lysophosphatidic acid: relevance to tumor growth and angiogenesis // Int. J. Mol. Med.-2003.-Vol.12, №4.-P.633-641.
111. Suzuki H., Kanagawa H., Nishihira J. Evidence for the presence of macrophage migration inhibitory factor in murine reproductive organs and early embryos // Immunol. Lett.-1996.-Vol.51, №3.-P.141-147.
112. Swope M.D., Lolis E. Macrophage migration inhibitory factor: cytokine, hormone, or enzyme? // Rev. Physiol. Biochem. Pharmacol.-1999.-Vol.139.-P.1-32.
113. Swope M., Sun H.W., Blake P.R., Lolis E. Direct link between cytokine activity and a catalytic site for macrophage migration inhibitory factor // EMBO J.-1998.-Vol.17, №13.-P.3534-3541.
114. Swope M.D., Sun H.W., Klockow B., Blake P., Lolis E. Macrophage migration inhibitory factor inter- actions with glutathione and S-hexylglutathione // J. Biol. Chem.-1998.-Vol.273,№24.-P.14877-14884.
115. Takahashi M., Nishihira J., Shimpo M., Mizue Y., Ueno S., Mano H., Kobayashi E., Ikeda U., Shimada K. Macrophage migration inhibitory factor as a redox-sensitive cytokine in cardiac myocytes // Cardiovasc. Res.-2001.-Vol.52, №3.-P.438-445.
116. Takase H., Sugita S., Rhee D.J., Imai Y., Taguchi C., Sugamoto Y., Tagawa Y., Nishihira J., Russell P., Mochizuki M. The presence of macrophage migration inhibitory factor in human trabecular meshwork and its upregulatory effects on the T helper 1 cytokine // Invest. Ophthalmol. Vis. Sci.-2002.-Vol.43, №8.- P.2691-2696.
117. Ueno M., Sugita T., Murakami T., Takata I. The novel anti-rheumatic drug TA-383 has a macrophage migration enhancing activity // Jpn. J. Pharmacol.- 1997.-Vol.74, №2.-P.221-224.
118. Vu T.K., Hung D.T., Wheaton V.I., Coughlin S.R. Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation // Cell-1991.Vol.64, №6.-P.1057-1068.
119. Vu T.K., Wheaton V.I., Hung D.T., Charo I., Coughlin S.R. Domains specifying thrombin-receptor interaction // Nature-1991.-Vol.353, №6345.-P.674-677.
120. Wadgaonkar R., Dudek S., Zaiman A., Linz-McGillem L., Verin A., Nurmukhambetova S., Romer L., Garcia J. Intracellular interaction of myosin light chain kinase with macrophage migration inhibition factor (MIF) in endothelium// J. Cell. Biochem.- 2005.- Vol. 95, № 4. – P. 849-858.
121. Waeber G., Calandra T., Bonny C., Bucala R. A role for the endocrine and pro-inflammatory mediator MIF in the control of insulin secretion during stress // Diabetes Metab. Res. Rev.-1999.-Vol.15, №1.-P.47-54.
122. Waeber G., Calandra T., Roduit R., Haefliger J.A., Bonny C., Thompson N., Thorens B., Temler E., Meinhardt A., Bacher M., Metz C.N., Nicod P., Bucala R. Insulin secretion is regulated by the glucose-dependent production of islet beta cell macrophage migration inhibitory factor // PNAS-1997.-Vol.94, №9.- P.4782-4787.
123. Watanabe H., Shimizu T., Nishihira J., Abe R., Nakayama T., Taniguchi M., Sabe H., Ishibashi T., Shimizu H. Ultraviolet A-induced production of matrix metalloproteinase-1 is mediated by macrophage migration inhibitory factor (MIF) in human dermal fibroblasts // J. Biol. Chem.-2004.-Vol.279, №3.-P.1676- 1683.
124. Watarai H., Nozawa R., Tokunaga A., Yuyama N., Tomas M., Hinohara A., Ishizaka K., Ishii Y. Posttranslational modification of the glycosylation inhibiting factor (GIF)gene product generates bioactive GIF // PNAS-2000.-Vol.97, №24.-P.13251-13256.
125. Weiser W.Y., Temple P.A., Witek-Giannotti J.S., Remold H.G., Clark S.C., David J.R. Molecular cloning of a cDNA encoding a human macrophage migration inhibitory factor // PNAS – 1989.-Vol.86.-P.7522-7526.
126. Willson D.F. Cytokine pharmasciences licenses anti-MIF technology to Baxter Healthcare Corporation // Cytokine PharmaSciences, Inc.-2003.
127. Wistow G.J., Shaughnessy M.P., Lee D.C., Hodin J., Zelenka P.S. A macrophage migration inhibitory factor is expressed in the differentiating cells of the eye lens // PNAS-1993.-Vol.90, №4.-P.1272-1275.
128. Wu J., Cunha F.Q., Liew F.Y., Weiser W.Y. IL-10 inhibits the synthesis of migration inhibitory factor and migration inhibitory factor-mediated macrophage activation // J. Immunol.-1993.-Vol.151, №8.-P.4325-4332.
129. Wymann D., Bluggel M., Kalbacher H., Blesken T., Akdis C.A., Meyer H.E., Blaser K. Human B cells secrete migration inhibition factor (MIF) and present a naturally processed MIF peptide on HLA-DRB1* *0405 by a FXXL motif // Immunology.-1999.-Vol.96, №1.-P.1-9.
130. Yasuda Y., Kasuya K., Nishihira J., Sasaki Y., Tsuchida A., Aoki T., Koyanagi Y. Induction of cell arrest by transfection of macrophage migration inhibitory factor antisense plasmid // Int. J. Mol. Med.-2002.- Vol.10, №4.-P.463-467.
131. Zwadlo G., Bruggen J., Gerhards G, Schlegel R., Sorg C. Two calcium-binding proteins associated with specific stages of myeloid cell differentiation are expressed by subsets of macrophages in inflammatory tissues.// Cli. Exp. Immunol.-1988.-V.72.-No3.-P.510- 515.
132. А.С.Симбирцев. Цитокины - классификация и биологические функции // Цитокины и воспаление – 2004.- Т.3, №2.-С.16-22.
133. А.П. Суслов, О.Ю. Третьяков, М.В. Коноплева. Структурные и функциональные особенности MIF // Медицинская иммунология – 2004.-T.6, №3-5.-C.193-200.
Рецензия
Для цитирования:
Суслов А.П., Коноплева М.В., Третьяков О.Ю. ФУНДАМЕНТАЛЬНАЯ ИММУНОБИОЛОГИЯ ПРОВОСПАЛИТЕЛЬНЫХ ЦИТОКИНОВ И MIF. Медицинская иммунология. 2006;8(1):5-22. https://doi.org/10.15789/1563-0625-2006-1-5-22
For citation:
Suslov A.P., Konopleva M.V., Tretiakov O.Yu. FUNDAMENTAL IMMUNOBIOLOGY OF PRO-INFLAMMATORY CYTOKINES AND MIF. Medical Immunology (Russia). 2006;8(1):5-22. (In Russ.) https://doi.org/10.15789/1563-0625-2006-1-5-22
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