CYTOMETRIC ANALYSIS OF THE SPECTRUM SUBPOPULATION OF T LYMPHOCYTES IN THE EARLY FORMS OF CHRONIC BRAIN ISCHEMIA VETERANS OF MODERN WARS
https://doi.org/10.15789/1563-0625-2015-1-33-38
Abstract
Formation of the earliest forms of chronic brain ischemia veterans of modern wars accompanied by an increase in the systemic circulation of the population of T lymphocytes and monocytes, reflecting the activation of central mechanisms lymphopoiesis. In step vascular encephalopathy is an increase in circulating pool of T lymphocytes expressing the activation markers early positive reflecting readiness cells to IL-2 dependent proliferation. When progessirovanii chronic brain ischemia decreased levels of circulating T-regulatory cells, which may reflect a violation of self-tolerance in relation to brain antigens.
About the Authors
A. V. Zurochka
Institute of Immunology and Physiology, Ekaterinburg, Russian Federation
Russian Federation
Russian Federation
PhD, MD (Medicine), Professor, Leading Research Associate, Institute of Immunology and Physiology, Ekaterinburg, Russian Federation
E. V. Davydova
South Ural State Medical University 454005, Russian Federation, Chelyabinsk, Vorovskogo str., 64.
Russian Federation
Russian Federation
PhD (Medicine), Associate Professor, Department of Pathophysiology, South Ural State Medical University, Chelyabinsk, Russian Federation
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Review
For citations:
Zurochka A.V., Davydova E.V. CYTOMETRIC ANALYSIS OF THE SPECTRUM SUBPOPULATION OF T LYMPHOCYTES IN THE EARLY FORMS OF CHRONIC BRAIN ISCHEMIA VETERANS OF MODERN WARS. Medical Immunology (Russia). 2015;17(1):33-38. (In Russ.) https://doi.org/10.15789/1563-0625-2015-1-33-38
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