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TO THE QUESTION ABOUT IMMUNOLOGIES CRITERIAS OF EFFICIENCY OF ANTIVIRUS THERAPY OF A CHRONIC VIRUS HEPATITES C

https://doi.org/10.15789/1563-0625-2006-5-6-673-678

Abstract

Abstract. The group of patients in amount 45 person received the standard combined therapy by preparations of recombinant IFN-α in combination with ribavirin. The positive effect of standard antivirus treatment at patients with chronic HCV-infection associated with increase of level of IL-2, decrease of levels of TNF-α, IL-1α, IL-12р40, IL-12р70 and IL-10 in peripheral serum. It has allowed to use them as noninvasive markers of the steady virologic answer during treatment of a chronic HCV-infection.

About the Authors

L. Ph. Sklyar
ГОУ ВПО «Владивостокский государственный медицинский университет», Владивосток
Russian Federation


E. V. Markelova
ГОУ ВПО «Владивостокский государственный медицинский университет», Владивосток
Russian Federation


References

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Review

For citations:


Sklyar L.P., Markelova E.V. TO THE QUESTION ABOUT IMMUNOLOGIES CRITERIAS OF EFFICIENCY OF ANTIVIRUS THERAPY OF A CHRONIC VIRUS HEPATITES C. Medical Immunology (Russia). 2006;8(5-6):673-678. (In Russ.) https://doi.org/10.15789/1563-0625-2006-5-6-673-678

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