ZINC DEFICIENCY INDUCES FAS-MEDIATED APOPTOSIS
https://doi.org/10.15789/1563-0625-2005-4-441-443
Abstract
Abstract. The aim of the present research was to study the expression of Fas-receptor and differentiation antigens CD3, CD4, CD8, CD16, CD20 on mononuclear cells of peripheral blood in the group of people with asimptomatic Zn-deficiency caused by geochemical conditions (the Zn level in the soil < 0,1 mg/kg and in human diet 9,1 mg /d at norm 15 mg/d). Simultaneously, we estimated lymphocyte proliferative activity characterizing the cell functional state contrary to apoptosis. We found the association of Zn - deficiency with insufficiency of the T-cell compartment of the immune system most likely caused by accelerated apoptosis of T-lymphocytes.
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Review
For citations:
Karzakova L.M. ZINC DEFICIENCY INDUCES FAS-MEDIATED APOPTOSIS. Medical Immunology (Russia). 2005;7(4):441-443. (In Russ.) https://doi.org/10.15789/1563-0625-2005-4-441-443
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