DIAGNOSTIC AND PREDICTIVE VALUE OF TNF Α, IL-8 AND IL-6 ASSAYS IN THE PATIENTS WITH MYCOPLASMA-ASSOCIATED PNEUMONIAS
https://doi.org/10.15789/1563-0625-2007-4-5-519-522
Abstract
Abstract. We have observed 128 patients with non-nosocomial pneumonias. Bacterial microflora was isolated in 22.6 per cent of entire group. 17 per cent of the samples were seropositive for Mycoplasma pneumoniae, along with detectable DNA specific for this causal agent. In 25 per cent of the patients, isolation of bacterial microflora was associated with positive antibody titers to Mycoplasma pneumoniae. Serum contents of cytokines (TNFα, IL-8, IL-6) have been studied in the patients. A positive correlation was found between increased cytokine levels and severity of the disease.
About the Authors
T. I. Dolgikh
Омская государственная медицинская академия
Russian Federation
Russian Federation
V. I. Sovalkin
Омская государственная медицинская академия
Russian Federation
Russian Federation
I. V. Menshchikova
Областная клиническая больница, г. Омск
Russian Federation
Russian Federation
References
1. Хаитов Р.М., Игнатьева Г.А., Сидорович И.Г. Иммунология. – М., 2000. – 430 с.
2. Чучалин А.Г., Синопальников А.И., Чернеховская Н.Е. Пневмония. – М.: Экономика и информатика, 2002. – 480 с.
3. Чучалин А.Г. Диагностика и лечение пневмоний с позиций медицины доказательств // Consilium medicum. – 2002. – № 4. – С. 12.
4. American Thoracic Society. Guidelines for the management of adults with community-acquired pneumonia. Diagnosis, assessment of severity, antimicrobial therapy and prevention // Am. J. Respir. Crit. Care Med. – 2001. – Vol. 163. – P. 1730-1754.
Review
For citations:
Dolgikh T.I., Sovalkin V.I., Menshchikova I.V. DIAGNOSTIC AND PREDICTIVE VALUE OF TNF Α, IL-8 AND IL-6 ASSAYS IN THE PATIENTS WITH MYCOPLASMA-ASSOCIATED PNEUMONIAS. Medical Immunology (Russia). 2007;9(4-5):519-522. (In Russ.) https://doi.org/10.15789/1563-0625-2007-4-5-519-522
Views:
910
Email this article 