CLINICAL AND EPIDEMIOLOGICAL ASPECTS OF PRIMARY IMMUNODEFICIENCY DISEASES (PID) AND EARLY DIAGNOSIS OPTIONS
https://doi.org/10.15789/1563-0625-2017-5-505-512
Abstract
Neonatal screening for primary immunodeficiencies (PID) provides a unique opportunity for early detection of moderate to severe immune disorders. Thus, the patients could be provided with best available therapy, due to effective treatment according to updated PID management guidelines. Clinical outcomes of recently implemented screening programs have demonstrated high sensitivity and specificity of the diagnostic techniques used and good survival rates. The existing evidence provides a strong basis for inclusion of PID screening into general Russian neonatal screening program.
About the Authors
I. A. Korsunskiy
ГБУЗ «Детская городская больница № 9 имени Г.Н. Сперанского ДЗМ».
Russian Federation
Competing Interests: Moscow City Pediatric G. Speransky Clinical Hospital No. 9.
Russian Federation
Korsunskiy I.A., PhD (Medicine), Head, Center of Pediatric Immunology and Allergy, Moscow City Pediatric G. Speransky Clinical Hospital No. 9.
Moscow.
Competing Interests: Moscow City Pediatric G. Speransky Clinical Hospital No. 9.
M. A. Gordukova
Moscow City Pediatric G. Speransky Clinical Hospital No. 9.
Russian Federation
Russian Federation
Gordukova M.A., Doctor for Clinical Laboratory Diagnostics, Moscow City Pediatric G. Speransky Clinical Hospital No. 9.
Moscow.
D. B. Munblit
The First Moscow I. Sechenov Medical University; Imperial College London.
Russian Federation
Munblit D.B., PhD (Medicine), Honorary Research Associate, Department of Pediatrics and Infections in Children, Pediatric Faculty, The First Moscow I. Sechenov Medical University, Moscow, Russian Federation; Imperial College London, London
Russian Federation
Munblit D.B., PhD (Medicine), Honorary Research Associate, Department of Pediatrics and Infections in Children, Pediatric Faculty, The First Moscow I. Sechenov Medical University, Moscow, Russian Federation; Imperial College London, London
I. G. Kozlov
Federal D. Rogachev Research and Clinical Center for Pediatric Hematology, Oncology and Immunology; Russian National Research N.I. Pirogov Medical University.
Russian Federation
Russian Federation
Kozlov I.G., PhD, MD (Medicine), Professor, Head, Department of Pharmacology, Russian National N.I. Pirogov Research Medical University; Chief, Laboratory of Experimental and Clinical Pharmacology, Federal D. Rogachev Research and Clinical Centre of Pediatric Hematology, Oncology, and Immunology.
Moscow.
A. P. Prodeus
Moscow City Pediatric G. Speransky Clinical Hospital No. 9; Federal D. Rogachev Research and Clinical Center for Pediatric Hematology, Oncology and Immunology; Russian National Research N.I. Pirogov Medical University.
Russian Federation
Russian Federation
Prodeus A.P., PhD, MD (Medicine), Professor, Head, Department of Pediatrics, Russian National Research N.I. Pirogov Medical University; Head of Department of Immunology and Rheumatology, Federal D. Rogachev Research and Clinical Center for Pediatric Hematology, Oncology and Immunology; Moscow City Pediatric G. Speransky Clinical Hospital No. 9.
Moscow.
A. A. Korsunskiy
Moscow City Pediatric G. Speransky Clinical Hospital No. 9; The First Moscow I. Sechenov Medical University.
Russian Federation
Russian Federation
Korsunskiy A.A., PhD, MD (Medicine), Professor, Head, Department of Pediatrics and Infections in Children, Pediatric Faculty, The First Moscow I. Sechenov Medical University; Moscow City Pediatric G. Speransky Clinical Hospital No. 9.
Moscow.
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Korsunskiy I.A., Gordukova M.A., Munblit D.B., Kozlov I.G., Prodeus A.P., Korsunskiy A.A. CLINICAL AND EPIDEMIOLOGICAL ASPECTS OF PRIMARY IMMUNODEFICIENCY DISEASES (PID) AND EARLY DIAGNOSIS OPTIONS. Medical Immunology (Russia). 2017;19(5):505-512. (In Russ.) https://doi.org/10.15789/1563-0625-2017-5-505-512
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