References

mimmun

Медицинская иммунология

Medical Immunology (Russia)

1563-06252313-741X

SPb RAACI

10.15789/1563-0625-2017-5-505-512

mimmun-1349

Research Article

ОБЗОРЫ

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КЛИНИЧЕСКИЕ И ЭПИДЕМИОЛОГИЧЕСКИЕ АСПЕКТЫ ПЕРВИЧНЫХ ИММУНОДЕФИЦИТНЫХ СОСТОЯНИЙ И ИХ РАННЕГО ОБНАРУЖЕНИЯ

CLINICAL AND EPIDEMIOLOGICAL ASPECTS OF PRIMARY IMMUNODEFICIENCY DISEASES (PID) AND EARLY DIAGNOSIS OPTIONS

Корсунский

И. А.

Korsunskiy

I. A.

Корсунский И.А. – кандидат медицинских наук, заведующий клиникодиагностическим центром детской иммунологии и аллергологии ГБУЗ «Детская городская больница № 9 имени Г.Н. Сперанского ДЗМ».

Москва.

Korsunskiy I.A., PhD (Medicine), Head, Center of Pediatric Immunology and Allergy, Moscow City Pediatric G. Speransky Clinical Hospital No. 9.

Moscow.

iliakors@gmail.com

Гордукова

М. А.

Gordukova

M. A.

Гордукова М.А. – врач клинической и лабораторной диагностики ГБУЗ «Детская городская больница № 9 имени Г.Н. Сперанского ДЗМ».

Москва.

Gordukova M.A., Doctor for Clinical Laboratory Diagnostics, Moscow City Pediatric G. Speransky Clinical Hospital No. 9.

Moscow.

Мунблит

Д. Б.

Munblit

D. B.

Мунблит Д.Б. – кандидат медицинских наук, научный сотрудник, кафедра педиатрии и детских инфекционных болезней педиатрического факультета ФГАОУ ВО «Первый Московский государственный медицинский университет имени И.М. Сеченова», Москва; Имперский колледж Лондона, Лондон, Великобритания

Munblit D.B., PhD (Medicine), Honorary Research Associate, Department of Pediatrics and Infections in Children, Pediatric Faculty, The First Moscow I. Sechenov Medical University, Moscow, Russian Federation; Imperial College London, London

Козлов

И. Г.

Kozlov

I. G.

Козлов И.Г. – доктор медицинских наук, профессор, заведующий кафедрой фармакологии ГБОУ ВПО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Министерства здравоохранения РФ; заведующий лабораторией экспериментальной и клинической фармакологии ФГБУ «Федеральный научно-практический центр детской гематологии, онкологии и иммунологии им. Д. Рогачева».

Москва.

Kozlov I.G., PhD, MD (Medicine), Professor, Head, Department of Pharmacology, Russian National N.I. Pirogov Research Medical University; Chief, Laboratory of Experimental and Clinical Pharmacology, Federal D. Rogachev Research and Clinical Centre of Pediatric Hematology, Oncology, and Immunology.

Moscow.

Продеус

А. П.

Prodeus

A. P.

Продеус А.П. – доктор медицинских наук, профессор, заведующий кафедрой педиатрии, ФГБОУ ВО «Российский национальный исследовательский медицинский университет имени Н.И. Пирогова»; руководитель отделения иммунологии и ревматологии, ФГБУ «Федеральный научнопрактический центр детской гематологии, онкологии и иммунологии им. Д. Рогачева»; ГБУЗ «Детская городская больница № 9 имени Г.Н. Сперанского ДЗМ».

Москва.

Prodeus A.P., PhD, MD (Medicine), Professor, Head, Department of Pediatrics, Russian National Research N.I. Pirogov Medical University; Head of Department of Immunology and Rheumatology, Federal D. Rogachev Research and Clinical Center for Pediatric Hematology, Oncology and Immunology; Moscow City Pediatric G. Speransky Clinical Hospital No. 9.

Moscow.

Корсунский

А. А.

Korsunskiy

A. A.

Корсунский А.А. – доктор медицинских наук, профессор, заведующий кафедрой педиатрии и детских инфекционных болезней педиатрического факультета ФГАОУ ВО «Первый Московский государственный медицинский университет имени И.М. Сеченова»; ГБУЗ «Детская городская больница № 9 имени Г.Н. Сперанского ДЗМ».

Москва.

Korsunskiy A.A., PhD, MD (Medicine), Professor, Head, Department of Pediatrics and Infections in Children, Pediatric Faculty, The First Moscow I. Sechenov Medical University; Moscow City Pediatric G. Speransky Clinical Hospital No. 9.

Moscow.

ГБУЗ «Детская городская больница № 9 имени Г.Н. Сперанского ДЗМ».Russian Federation

ГБУЗ «Детская городская больница № 9 имени Г.Н. Сперанского ДЗМ».РоссияMoscow City Pediatric G. Speransky Clinical Hospital No. 9.Russian Federation

ФГАОУ ВО «Первый Московский государственный медицинский университет имени И.М. Сеченова»; Имперский колледж Лондона.РоссияThe First Moscow I. Sechenov Medical University; Imperial College London.Russian Federation

ГБОУ ВПО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Министерства здравоохранения РФ; ФГБУ «Федеральный научно-практический центр детской гематологии, онкологии и иммунологии им. Д. Рогачева».РоссияFederal D. Rogachev Research and Clinical Center for Pediatric Hematology, Oncology and Immunology; Russian National Research N.I. Pirogov Medical University.Russian Federation

ФГБОУ ВО «Российский национальный исследовательский медицинский университет имени Н.И. Пирогова»; ФГБУ «Федеральный научнопрактический центр детской гематологии, онкологии и иммунологии им. Д. Рогачева»; ГБУЗ «Детская городская больница № 9 имени Г.Н. Сперанского ДЗМ».РоссияMoscow City Pediatric G. Speransky Clinical Hospital No. 9; Federal D. Rogachev Research and Clinical Center for Pediatric Hematology, Oncology and Immunology; Russian National Research N.I. Pirogov Medical University.Russian Federation

ФГАОУ ВО «Первый Московский государственный медицинский университет имени И.М. Сеченова»; ГБУЗ «Детская городская больница № 9 имени Г.Н. Сперанского ДЗМ».РоссияMoscow City Pediatric G. Speransky Clinical Hospital No. 9; The First Moscow I. Sechenov Medical University.Russian Federation

2017

18102017

195505512

2017

Корсунский И.А., Гордукова М.А., Мунблит Д.Б., Козлов И.Г., Продеус А.П., Корсунский А.А.

Korsunskiy I.A., Gordukova M.A., Munblit D.B., Kozlov I.G., Prodeus A.P., Korsunskiy A.A.

Данная работа распространяется под лицензией Creative Commons Attribution 4.0.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://www.mimmun.ru/mimmun/article/view/1349

Неонатальный скрининг первичных иммунодефицитных состояний делает возможным раннее обнаружение тяжелых и среднетяжелых поражений иммунной системы, а эффективность современных протоколов лечения этой группы заболеваний несомненна. Результаты нескольких запущенных в последние годы скрининговых программ показывают высокую чувствительность и специфичность скрининга, высокую выживаемость пациентов, что, в свою очередь, доказывает необходимость введения первичных иммунодефицитных состояний в программу неонатального скрининга России.

Neonatal screening for primary immunodeficiencies (PID) provides a unique opportunity for early detection of moderate to severe immune disorders. Thus, the patients could be provided with best available therapy, due to effective treatment according to updated PID management guidelines. Clinical outcomes of recently implemented screening programs have demonstrated high sensitivity and specificity of the diagnostic techniques used and good survival rates. The existing evidence provides a strong basis for inclusion of PID screening into general Russian neonatal screening program.

ПИДТКИНнеонатальный скринингTRECKREC

primary immune deficiencySCIDNBSTRECKREC

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The authors declare that there are no conflicts of interest present.