CLINICAL DIAGNOSTIC VALUE OF AUTOANTIBODIES IN THE DIAGNOSIS OF AUTOIMMUNE LIVER DISEASES
https://doi.org/10.15789/1563-0625-2015-1-93-96
Abstract
We are studied the 15 patients with autoimmune liver diseases and 36 patients without autoimmune pathology found the diagnostic value of antinuclear and antimitochondrial autoantibodies (AMA-M2) tests, and antibodies to asialoglycoprotein receptor (anti-ASGPR). Based on the ROC analysis showed that the diagnostic sensitivity and diagnostic specificity of AMA-M2 was 73% and 100% and for anti-ASGPR – 60% and 77%, respectively. Therefore, the test for anti-ASGPR in autoimmune diseases of the liver showed no advantages over standart tests, and its using in clinical practice requires clarification.
About the Authors
V. V. Bazarnyi
Ural State Medical University
620028, Russian Federation, Ekaterinburg, Repin str., 3.
Russian Federation
Russian Federation
PhD, MD (Medicine), Professor, Ural State Medical University, Ekaterinburg, Russian Federation
E. Yu. Mikhailova
Ural State Medical University
620028, Russian Federation, Ekaterinburg, Repin str., 3.
Russian Federation
Russian Federation
Junior Research Associate, Ural State Medical University, Ekaterinburg, Russian Federation
E. A. Partylova
Ural State Medical University
620028, Russian Federation, Ekaterinburg, Repin str., 3.
Russian Federation
Russian Federation
PhD (Medicine), Research Associate, Ural State Medical University, Ekaterinburg, Russian Federation
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Review
For citations:
Bazarnyi V.V., Mikhailova E.Yu., Partylova E.A. CLINICAL DIAGNOSTIC VALUE OF AUTOANTIBODIES IN THE DIAGNOSIS OF AUTOIMMUNE LIVER DISEASES. Medical Immunology (Russia). 2015;17(1):93-96. (In Russ.) https://doi.org/10.15789/1563-0625-2015-1-93-96
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