FEATURES OF IMMUNE RESPONSE IN PATIENTS WITH DIFFERENT HISTOLOGICAL TYPES OF RENAL CELL CARCINOMA
https://doi.org/10.15789/1563-0625-2013-4-375-382
Abstract
Abstract. We have examined ninety-three patients with locally advanced renal cell cancer at the age of 45 to 55 years. Immunological testing was performed before radical nephrectomy and 14 days after surgery. The cellular and humoral immune parameters and cell chemiluminescence were studied both at baseline and in stimulated cells. We found changes of immunophenotypic profile of blood lymphocytes, serum immunoglobulin indexes and chemiluminescence response of blood neutrophils, dependent on tumor histology.
About the Authors
L. М. Kurtasova
Krasnoyarsk State V.F. Voyno-Yasenetsky Medical University, Krasnoyarsk
Russian Federation
Russian Federation
PhD, MD, Professor, Clinical Immunology Department
660022, P. Zhelesniak str., 1. Phone: 7 (391) 220-06-28. Fax: 7 (391) 221-16-38
E. A. Shkapova
Krasnoyarsk A.I. Kryzhanivskyi Regional Clinical Oncological Center, Krasnoyarsk
Russian Federation
Russian Federation
PhD (Biology), Laboratory of Immunology
R. A. Zukov
Krasnoyarsk State V.F. Voyno-Yasenetsky Medical University, Krasnoyarsk
Russian Federation
Russian Federation
PhD (Medicine), Assistant Professor, Oncology and Radiotherapy Department
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Review
For citations:
Kurtasova L.М., Shkapova E.A., Zukov R.A. FEATURES OF IMMUNE RESPONSE IN PATIENTS WITH DIFFERENT HISTOLOGICAL TYPES OF RENAL CELL CARCINOMA. Medical Immunology (Russia). 2013;15(4):375-382. (In Russ.) https://doi.org/10.15789/1563-0625-2013-4-375-382
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