DIVERSE PEACH ALLERGY: SENSITIZATION TO MOLECULAR COMPONENTS OF ALLERGENS FROM PRUNUS PERSICA
https://doi.org/10.15789/1563-0625-2013-3-215-226
Abstract
Abstract. Results of immunological and molecular biology investigations over last decades allowed clear to specify mechanisms of development and clinical features of allergic reactions to food of plant origin, including allergies to fruits Prunus persica - peaches and nectarines. The article contains the analysis of literature data on allergic reactions to peach, as well as clinical observations of the patients with this kind of allergy and of the results of the component component resolved diagnosis, ISAC ImmunoCAP, conducted by these patients. The collected data allow to detect two fundamentally different types of allergic reactions to Prunus persica. This is due to sensitization to allergen Pru p 3 severe systemic reaction, and due to sensitization to Pru p 1 or Pru p 4 – local response, manifesting oral allergy syndrome and associated with sensitization to pollen allergens.
About the Authors
M. A. Mokronosova
I.I. Mechnikov’s Research Institute of Vaccines and Sera RAMS, Moscow
Russian Federation
Russian Federation
PhD, MD (Medicine), Professor, Chief, Laboratory of Clinical Allergology
105064, Malyy Kazennyy lane, 5а. Phone: 7 (495) 917-08-91. Fax: 7 (495) 917-49-00
E. S. Korovkina
I.I. Mechnikov’s Research Institute of Vaccines and Sera RAMS, Moscow
Russian Federation
Russian Federation
PhD (Medicine), Senior Research Associate, Laboratory of Clinical Allergology
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Review
For citations:
Mokronosova M.A., Korovkina E.S. DIVERSE PEACH ALLERGY: SENSITIZATION TO MOLECULAR COMPONENTS OF ALLERGENS FROM PRUNUS PERSICA. Medical Immunology (Russia). 2013;15(3):215-226. (In Russ.) https://doi.org/10.15789/1563-0625-2013-3-215-226
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