ГУМОРАЛЬНЫЕ И КЛЕТОЧНЫЕ ФАКТОРЫ ИММУНИТЕТА ПРИ ИНФАРКТЕ МИОКАРДА
https://doi.org/10.15789/1563-0625-2010-6-477-484
Аннотация
Данные, представленные в обзоре, характеризуют ключевую роль гуморальных и клеточных факторов иммунитета, выявляемых в постинфарктном периоде. Согласно этим данным, иммунореактивность может определять уровень повреждения миокарда и последующее течение болезни.
Об авторах
В. И. СеледцовРоссия
Л. С. Литвинова
Россия
И. А. Селедцова
Российский государственный университет им. И. Канта, г. Калининград
Россия
Россия
Е. В. Кириенкова
Российский государственный университет им. И. Канта, г. Калининград
Россия
Россия
В. В. Шуплецова
Российский государственный университет им. И. Канта, г. Калининград
Россия
Россия
Список литературы
1. Китаев М.И., Миррахимов М.М. Иммунология коронарной болезни сердца. Очерки. -Бишкек, 2007. -197 с.
2. Abbasi S.H., Boroumand M.A. Expanded network of inflammatory markers of atherogenesis: where are we now?//Open Cardiovasc Med. J. -2010. -Vol. 4. -P. 38-44.
3. Albelda S.M., Smith C.W., Ward P.A. Adhesion molecules and inflammatory injury//Faseb. J. -1994. -Vol. 8. -P. 504-512.
4. Bassols A., Massague J. Transforming growth factor beta regulates the expression and structure of extracellular matrix chondroitin/dermatan sulfate proteoglycans//J. Biol. Chem. -1988. -Vol. 263. -P. 3039-3045.
5. Berthonneche C., Sulpice T., Boucher F., Gouraud L., de Leiris J., O'Connor S.E., Herbert J.M., Janiak P. New insights into the pathological role of TNF-alpha in early cardiac dysfunction and subsequent heart failure after infarction in rats//Am. J. Physiol. Heart. Circ. Physiol. -2004. -Vol. 287. -P. 340-350.
6. Binder C.J., Horkko S., Dewan A., Chang M.K., Kieu E.P., Goodyear C.S., Shaw P.X., Palinski W., Witztum J.L., Silverman G.J. Pneumococcal vaccination decreases atherosclerotic lesion formation: molecular mimicry between Streptococcus pneumoniae and oxidized LDL//Nat Med. -2003. -Vol. 9. -P. 736-743.
7. Bujak M., Dobaczewski M., Chatila K., Mendoza L.H., Na L., Reddy A, Frangogiannis NG. Interleukin-1 Receptor type I signaling critically regulates infarct healing and cardiac remodeling//Am. J. Pathol. -2008. -Vol. 173. -P. 57-67.
8. Buono C., Binder C.J., Stavrakis G., Witztum J.L., Glimcher L.H., Lichtman A.H. T-bet deficiency reduces atherosclerosis and alters plaque antigen-specific immune responses//Proc. Natl. Acad. Sci. USA. -2005. -Vol. 102. -P. 1596-1601.
9. Caligiuri G., Nicoletti A., Poirier B., Hansson G.K. Protective immunity against atherosclerosis carried by B cells of hypercholesterolemic mice//J. Clin. Invest. -2002. -Vol. 109. -P. 745-753.
10. Carding S.R., Egan P.J. Gamm-adelta T cells: functional plasticity and heterogeneity//Nat Rev Immunol. -2002. -Vol. 2. -P. 336-345.
11. Dean R.G., Balding L.C., Candido R., Burns W.C., Cao Z., Twigg S.M., Burrell L.M. Connective tissue growth factor and cardiac fibrosis after myocardial infarction//J. Histochem. Cytochem. -2005. -Vol. 53. -P. 1245-1256.
12. Dewald O., Ren G., Duerr G.D., Zoerlein M., Klemm C., Gersch C., Tincey S., Michael L.H., Entman M.L., Frangogiannis N.G. Of mice and dogs: species-specific differences in the inflammatory response following myocardial infarction//Am. J. Pathol. -2004. -Vol. 164. -P. 665-677.
13. Dhawan S.S., Quyyumi A.A. Rheumatoid arthritis and cardiovascular disease//Curr Atheroscler Rep. -2008. -Vol. 10. -P. 128-133.
14. Doria A., Iaccarino L., Sarzi-Puttini P., Atzeni F., Turriel M., Petri M. Cardiac involvement in systemic lupus erythematosus//Lupus. -2005. -Vol. 14. -P. 683-686.
15. Edwards D.R., Murphy G., Reynolds J.J., Whitham S.E., Docherty A.J., Angel P., Heath J.K. Transforming growth factor beta modulates the expression of collagenase and metalloproteinase inhibitor//Embo J. -1987. -Vol. 6. -P. 1899-1904.
16. Elsheikh E., Sylvén C., Henareh L. Anti-endothelial cell antibodies are increased in patients with previous myocardial infarction//Scand Cardiovasc J. -2010. -In press.
17. Engel D., Peshock R., Armstong R.C., Sivasubramanian N., Mann D.L. Cardiac myocyte apoptosis provokes adverse cardiac remodeling in transgenic mice with targeted TNF overexpression//Am J Physiol Heart Circ Physiol. -2004. -Vol. 287. -P. 1303-1311.
18. Fairweather D., Cihakova D. Alternatively activated macrophages in infection and autoimmunity//J. Autoimmun. -2009. -Vol. 33. -P. 222-230.
19. Frangogiannis N.G. The immune system and cardiac repair//Pharmacol Res. -2008. -Vol. 58. -P. 88-111.
20. Dreyer W.J., Michael L.H., Nguyen T., Smith C.W., Anderson D.C., Entman M.L., Rossen R.D. Kinetics of C5a release in cardiac lymph of dogs experiencing coronary artery ischemia-reperfusion injury//Circ Res. -1992. -Vol. 71. -P. 518-1524.
21. Frangogiannis N.G., Lindsey M.L., Michael L.H., Youker K.A., Bressler R.B., Mendoza L.H., Spengler R.N., Smith C.W., Entman M.L. Resident cardiac mast cells degranulate and release preformed TNF alpha, initiating the cytokine cascade in experimental canine myocardial ischemia/reperfusion//Circulation. -1998. -Vol. 98. -P. 699-710.
22. Frangogiannis N.G., Perrard J.L., Mendoza L.H., Burns A.R., Lindsey M.L., Ballantyne C.M., Michael L.H., Smith C.W., Entman M.L. Stem cell factor induction is associated with mast cell accumulation after canine myocardial ischemia and reperfusion//Circulation. -1998. -Vol. 98. -P. 687-698.
23. Gabriel S.E., Crowson C.S., Kremers H.M., Doran M.F., Turesson C., O'Fallon W.M. Survival in rheumatoid arthritis: a population-based analysis of trends over 40 years//Arthritis Rheum. -2003. -Vol. 48. -P. 54-58.
24. Grammer T.B., Fuchs D., Boehm B.O., Winkelmann B.R., Maerz W. Neopterin as a predictor of total and cardiovascular mortality in individuals undergoing angiography in the Ludwigshafen Risk and Cardiovascular Health study//Clin. Chem. -2009. -Vol. 55. -P. 1135-1146.
25. Griendling K.K., FitzGerald G.A. Oxidative stress and cardiovascular injury: Part I: basic mechanisms and in vivo monitoring of ROS//Circulation. -2003. -Vol. 108. -P. 912-1916.
26. Guillen I., Blanes M., Gomez-Lechon M.J., Castell J.V. Cytokine signaling during myocardial infarction: sequential appearance of IL-1 beta and IL-6//Am. J. Physiol. -1995. -Vol. 269. -P. 229-235.
27. Haas M.S., Alicot E.M., Schuerpf F., Chiu I., Li J., Moore F.D., Carroll M.C. Blockade of self-reactive IgM significantly reduces injury in a murine model of acute myocardial infarction//Cardiovasc Res. -2010. -Vol. 23. -P. 34-39.
28. Hensley K., Robinson K.A., Gabbita S.P., Salsman S., Floyd R.A. Reactive oxygen species, cell signaling, and cell injury//Free Radic. Biol. Med. -2000. -Vol. 28. -P. 1456-1462.
29. Huber C., Batchelor J.R., Fuchs D., Hausen A., Lang A., Niederwieser D., Reibnegger G., Swetly P., Troppmair J., Wachter H. Immune response-associated production of neopterin. Release from macrophages primarily under control of interferon-gamma//J. Exp. Med. -1984. -Vol. 160. -P. 310-316.
30. Hwang M.W., Matsumori A., Furukawa Y., Ono K., Okada M., Iwasaki A., Hara M., Miyamoto T., Touma M., Sasayama S. Neutralization of interleukin-1beta in the acute phase of myocardial infarction promotes the progression of left ventricular remodeling//J. Am. Coll. Cardiol. -2001. -Vol. 38. -P. 1546-1553.
31. Jaeschke H., Smith C.W. Mechanisms of neutrophil-induced parenchymal cell injury//J. Leukoc. Biol. -1997. -Vol. 61. -P. 647-653.
32. Jo D.Y., Rafii S., Hamada T., Moore M.A. Chemotaxis of primitive hematopoietic cells in response to stromal cell-derived factor-1//J. Clin. Invest. -2000. -Vol. 105. -P. 101-111.
33. Kurrelmeyer K.M., Michael L.H., Baumgarten G., Taffet G.E., Peschon J.J., Sivasubramanian N., Entman M.L., Mann D.L. Endogenous tumor necrosis factor protects the adult cardiac myocyte against ischemic-induced apoptosis in a murine model of acute myocardial infarction//Proc Natl Acad Sci U S A. -2000. -Vol. 97. -P. 5456-5461.
34. Lachtermacher S., Esporcatte B.L., Montalvão F., Costa P.C., Rodrigues D.C., Belem L., Rabischoffisky A., Faria Neto H.C., Vasconcellos R., Iacobas S., Iacobas D.A., Dohmann H.F., Spray D.C., Goldenberg R.C., Campos-de-Carvalho A.C. Cardiac gene expression and systemic cytokine profile are complementary in a murine model of post-ischemic heart failure//Braz. J. Med. Biol. Res. -2010. -Vol. 43. -P. 377-389.
35. Laiho M., Saksela O., Andreasen P.A., Keski-Oja J. Enhanced production and extracellular deposition of the endothelial-type plasminogen activator inhibitor in cultured human lung fibroblasts by transforming growth factor-beta//J. Cell Biol. -1986. -Vol. 103. -P. 2403-2410.
36. Laurat E., Poirier B., Tupin E., Caligiuri G., Hansson G.K., Bariety J., Nicoletti A. In vivo downregulation of T helper cell 1 immune responses reduces atherogenesis in apolipoprotein E-knockout mice//Circulation. -2001. -Vol. 104. -P. 197-202.
37. Letterio J.J., Roberts A.B. Regulation of immune responses by TGF-beta. Annu Rev. Immunol. -1998. -Vol. 16. -P. 137-161.
38. Liang K.P., Kremers H.M., Crowson C.S., Snyder M.R., Therneau T.M., Roger V.L., Gabriel S.E. Autoantibodies and the risk of cardiovascular events//J. Rheumatol. -2009. -Vol. 36. -P. 2462-2469.
39. Liao Y.H., Cheng X. Autoimmunity in myocardial infarction//Int. J. Cardiol. -2006. -Vol. 112. -P. 21-26.
40. Litt M.R., Jeremy R.W., Weisman H.F., Winkelstein J.A., Becker L.C. Neutrophil depletion limited to reperfusion reduces myocardial infarct size after 90 minutes of ischemia. Evidence for neutrophilmediated reperfusion injury//Circulation. -1989. -Vol. 80. -P. 1816-1827.
41. Maekawa N., Wada H., Kanda T., Niwa T., Yamada Y., Saito K., Fujiwara H., Sekikawa K., Seishima M. Improved myocardial ischemia/reperfusion injury in mice lacking tumor necrosis factor-alpha//J. Am. Coll. Cardiol. -2002. -Vol. 39. -P. 22-1235.
42. Mallat Z., Heymes C., Ohan J., Faggin E., Lesèche G., Tedgui A. Expression of interleukin-10 in advanced human atherosclerotic plaques//Arterioscler Thromb Vasc Biol. -1999. -Vol. 19. -P. 611-616.
43. Martinez F.O., Sica A., Mantovani A., Locati M. Macrophage activation and polarization//Front Biosci. -2008. -Vol. 13. -P. 453-461.
44. Monden Y., Kubota T., Tsutsumi T., Inoue T., Kawano S., Kawamura N., Ide T., Egashira K., Tsutsui H., Sunagawa K. Soluble TNF receptors prevent apoptosis in infiltrating cells and promote ventricular rupture and remodeling after myocardial infarction//Cardiovasc Res. -2007. -Vol. 73. -P. 794-805.
45. Packard R.R., Lichtman A.H., Libby P. Innate and adaptive immunity in atherosclerosis//Semin Immunopathol. -2009. -Vol. 31. -P. 5-22.
46. Patel K.D., Zimmerman G.A., Prescott S.M., McEver R.P., McIntyre T.M. Oxygen radicals induce human endothelial cells to express GMP-140 and bind neutrophils//J. Cell Biol. -1991. -Vol. 112. -P. 749-759.
47. Rollins B.J. Monocyte chemoattractant protein 1: a potential regulator of monocyte recruitment in inflammatory disease//Mol. Med. Today. -1996. -Vol. 2. -P. 198-204.
48. Romson J.L., Hook B.G., Kunkel S.L., Abrams G.D., Schork M.A., Lucchesi B.R. Reduction of the extent of ischemic myocardial injury by neutrophil depletion in the dog//Circulation. -1983. -Vol. 67. -P. 1016-1023.
49. Schulte S., Sukhova G.K., Libby P. Genetically programmed biases in Th1 and Th2 immune responses modulate atherogenesis//Am. J. Pathol. -2008. -Vol. 172. -P. 1500-1508.
50. Sellak H., Franzini E., Hakim J., Pasquier C. Reactive oxygen species rapidly increase endothelial ICAM-1 ability to bind neutrophils without detectable upregulation//Blood 1994. -Vol. 83. -P. 2669-2677.
51. Sen C.K., Packer L. Antioxidant and redox regulation of gene transcription//FASEB J. -1996. -Vol. 10. -P. 709-720.
52. Shingu M., Nonaka S., Nishimukai H., Nobunaga M., Kitamura H., Tomo-Oka K. Activation of complement in normal serum by hydrogen peroxide and hydrogen peroxide-related oxygen radicals produced by activated neutrophils//Clin Exp Immunol. -1992. -Vol. 90. -P. 72-78.
53. Song C., Shen Y., Yamen E., Hsu K., Yan W., Witting P., Geczy C., Freedman S. Serum amyloid A may potentiate prothrombotic and proinflammatory events in acute coronary syndromes//Atherosclerosis. -2009. -Vol. 202. -P. 596-604.
54. Stemme S., Faber B., Holm J., Wiklund O., Witztum J.L., Hansson G.K. T lymphocytes from human atherosclerotic plaques recognize oxidized low density lipoprotein//Proc Natl Acad Sci U S A. -1995. -Vol. 92. -P. 3893-3897.
55. Sugano M., Tsuchida K, Hata T, Makino N. In vivo transfer of soluble TNF-alpha receptor 1 gene improves cardiac function and reduces infarct size after myocardial infarction in rats//Faseb. J. -2004. -Vol. 18. -P. 911-913.
56. Suzuki K., Murtuza B., Smolenski R.T., Sammut I.A., Suzuki N., Kaneda Y., Yacoub M.H. Overexpression of interleukin-1 receptor antagonist provides cardioprotection against ischemia reperfusion injury associated with reduction in apoptosis//Circulation. -2001. -Vol. 104. -P. I308-I303.
57. Takami M., Terry V., Petruzzelli L. Signaling pathways involved in IL-8-dependent activation of adhesion through Mac-1//J. Immunol. -2002. -Vol. 168. -P. 4559-4566.
58. Tolar J., Wang X., Braunlin E., McElmurry R.T., Nakamura Y., Bell S., Xia L., Zhang J., Hu Q., Panoskaltsis-Mortari A., Zhang J., Blazar B.R. The host immune response is essential for the beneficial effect of adult stem cells after myocardial ischemia//Exp. Hematol. -2007. -Vol. 35. -P. 682-690.
59. Tupin E., Nicoletti A., Elhage R., Rudling M., Ljunggren H.G., Hansson G.K., Berne G.P. CD1d-dependent activation of NKT cells aggravates atherosclerosis // J. Exp. Med. - 2004. - Vol. 199. - P. 417-422.
60. Wollert KC., Drexler H. The role of interleukin-6 in the failing heart // Heart Fail Rev. - 2001. - Vol. 6. - P. 95-103.
61. Xia Y., Frangogiannis N.G. MCP-1/CCL2 as a therapeutic target in myocardial infarction and ischemic cardiomyopathy//Inflamm Allergy Drug Targets. -2007. -Vol. 6. -P. 101-107.
62. Xu Q., Kleindienst R., Waitz W., Dietrich H., Wick G. Increased expression of heat shock protein 65 coincides with a population of infiltrating T lymphocytes in atherosclerotic lesions of rabbits specifically responding to heat shock protein 65//J. Clin. Invest. -1993. -Vol. 91. -P. 2693-2702.
Рецензия
Для цитирования:
Селедцов В.И., Литвинова Л.С., Селедцова И.А., Кириенкова Е.В., Шуплецова В.В. ГУМОРАЛЬНЫЕ И КЛЕТОЧНЫЕ ФАКТОРЫ ИММУНИТЕТА ПРИ ИНФАРКТЕ МИОКАРДА. Медицинская иммунология. 2010;12(6):477-484. https://doi.org/10.15789/1563-0625-2010-6-477-484
For citation:
Seledtsov V.I., Litvinova L.S., Seledtsova I.A., Kirienkova E.V., Shupletsova V.V. HUMORAL AND CELLULAR IMMUNITY FACTORS IN MYOCARDIAL INFARCTION. Medical Immunology (Russia). 2010;12(6):477-484. (In Russ.) https://doi.org/10.15789/1563-0625-2010-6-477-484
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