QUANTITITATIVE CHANGES OF T-REGULATORY CELLS IN PATIENTS WITH POLIPOUS RHINOSINUSITIS TREATED BY NASAL GLUCOCORTICOSTEROIDS
https://doi.org/10.15789/1563-0625-2012-3-233-238
Abstract
Abstract. This work was aimed for studying immunity markers, especially, T-regulatory cells, in patients suffering from polypous rhinosinusitis and treated with nasal steroids, in frame of integrated preventive treatment. The study included fifteen patients of both sexes (18 to 60 years of age), and eighteen persons with difficulties of nasal breathing not associated with inflammatory events. T-regulatory cells were determined by a specific set of membrane receptors (CD4+, CD25+, CD127-). We have shown a significant reduction in T-regulatory cell contents prior to treatment, followed by their increase to normal levels in the course of therapy.
About the Authors
M. V. Semenov
Федеральное бюджетное государственное образовательное учреждение Высшего профессионального образования «Челябинская государственная медицинская академия Росздрава», г. Челябинск
Russian Federation
Russian Federation
A. V. Zurochka
Федеральное бюджетное государственное учреждение науки «Институт иммунологии и физиологии УрО РАН», г. Екатеринбург
Russian Federation
Russian Federation
V. A. Zurochka
Федеральное бюджетное государственное учреждение науки «Институт иммунологии и физиологии УрО РАН», г. Екатеринбург
Russian Federation
Russian Federation
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Review
For citations:
Semenov M.V., Zurochka A.V., Zurochka V.A. QUANTITITATIVE CHANGES OF T-REGULATORY CELLS IN PATIENTS WITH POLIPOUS RHINOSINUSITIS TREATED BY NASAL GLUCOCORTICOSTEROIDS. Medical Immunology (Russia). 2012;14(3):233-238. (In Russ.) https://doi.org/10.15789/1563-0625-2012-3-233-238
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