ANALYSIS OF INITIAL CLINICAL FEATURES OF PRIMARY IMMUNODEFICIENCIES IN ADULTS
https://doi.org/10.15789/1563-0625-2014-4-367-374
Abstract
At present, we are observing eighty-three adult patients with various primary immunodeficiencies (PID) of different origin. The aim of our study was to identify the optimal ways for early detection of such disorders. In this work, we present an analysis of initial clinical manifestations of PID in adults. It was revealed that the type of clinical manifestations is quite unique for individual cases. And the patients exhibit quite diverse clinical findings and course of the disorder, even within a single nosological entity. However, infectious syndrome prevailed among others manifestations. Combinations of complex clinical syndromes were not typical to initial PID pattern. We observed polytopic lesions within each single immunopathological syndrome.
About the Authors
I. A. Tuzankina
Institute of Clinical Immunology and Physiology, Ural Branch, Russian Academy of Sciences, Ekaterinburg
Regional Children Clinical Hospital № 1, Ekaterinburg
Russian Federation
Russian Federation
PhD, MD (Medicine), Main Research Associate, Institute of Clinical Immunology and Physiology, Ural Branch, Russian Academy of Sciences, Chief, Regional Center of Clinical Immunology, Chief immunologist (Sverdlovsk Region)
M. L. Karakina
Institute of Clinical Immunology and Physiology, Ural Branch, Russian Academy of Sciences, Ekaterinburg
Regional Children Clinical Hospital № 1, Ekaterinburg
Regional Clinical Hospital № 1, Ekaterinburg
Russian Federation
Russian Federation
PhD (Medicine), Research Associate, Institute of Immunology and Physiology, Ural Branch, Russian Academy of Sciences, Clinical Immunologist, Regional Children Clinical Hospital № 1 and Regional Clinical Hospital № 1
E. V. Vlasova
Regional Children Clinical Hospital № 1, Ekaterinburg
Russian Federation
Russian Federation
PhD (Medicine), Head, Consultation Service in Clinical Immunology, Regional Children Clinical Hospital № 1
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For citations:
Tuzankina I.A., Karakina M.L., Vlasova E.V. ANALYSIS OF INITIAL CLINICAL FEATURES OF PRIMARY IMMUNODEFICIENCIES IN ADULTS. Medical Immunology (Russia). 2014;16(4):367-374. (In Russ.) https://doi.org/10.15789/1563-0625-2014-4-367-374
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