IMMUNE STATE OF THE CHILDREN WITH BRONCHIAL ASTHMA FROM THE AMUR RIVER AND YAKUTIA REGIONS
https://doi.org/10.15789/1563-0625-2013-4-383-387
Abstract
Abstract. This work presents data on immune state of children with bronchial asthma living under environmental conditions of the Yakutia and Amur river regions. We examined immune functions of blood cells in 102 children with allergic diseases (bronchial asthma). Certain geographical and ecological conditions provide some specific change of immune system (immune deficiency) in the children with allergy. We have shown that the children with bronchial asthma exhibited immunological shifts in Th1/Th2 mechanism of immune responses, enhancement of humoral immune factors and deficiency of the phagocyte components.
About the Authors
M. V. Efimenko
Far Eastern State Medical University, Khabarovsk Branch, Far Eastern Center of Respiratory Physiology and Pathology, Russian Academy of Medical Sciences, Siberian Branch, Research Institute of Mother and Child Care, Khabarovsk
Russian Federation
Russian Federation
PhD (Medicine), Senior Research Associate, Laboratory of Endocrinology and Immunology Diagnostic, Chief, Laboratory of Integrated Research
M. I. Samsonova
Yakut Research Centre of Complex Medical Problems, Russian Academy of Medical Sciences, Siberian Branch, Yakutsk
Russian Federation
Russian Federation
PhD, MD (Medicine), Research Associate, Laboratory of Monitoring the Health Status of Children and Medical and Environmental Research
E. N. Suprun
Far Eastern State Medical University, Khabarovsk Branch, Far Eastern Center of Respiratory Physiology and Pathology, Russian Academy of Medical Sciences, Siberian Branch, Research Institute of Mother and Child Care, Khabarovsk
Russian Federation
Russian Federation
Assistant Professor, Department of Pediatrics, Faculty of Pediatrics
680021, Serysheva str., 74-49. Phone: 7 (4212) 25-76-85
T. E. Burtseva
Yakut Research Centre of Complex Medical Problems, Russian Academy of Medical Sciences, Siberian Branch, Yakutsk
Russian Federation
PhD, MD (Medicine), Deputy Director for Science
Russian Federation
PhD, MD (Medicine), Deputy Director for Science
L. E. Nikolaeva
Yakut Research Centre of Complex Medical Problems, Russian Academy of Medical Sciences, Siberian Branch, Yakutsk
Russian Federation
Russian Federation
Technician, Laboratory of Monitoring the Health Status of Children and Medical and Environmental Research
V. K. Kozlov
Far Eastern State Medical University, Khabarovsk Branch, Far Eastern Center of Respiratory Physiology and Pathology, Russian Academy of Medical Sciences, Siberian Branch, Research Institute of Mother and Child Care, Khabarovsk
Russian Federation
Russian Federation
PhD, MD (Medicine), Professor, Corresponding Member of the Russian Academy of Medical Sciences, Honored Worker of Science of the Russian Federation, Chief, Department of Pediatrics, Faculty of Pediatrics
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For citations:
Efimenko M.V., Samsonova M.I., Suprun E.N., Burtseva T.E., Nikolaeva L.E., Kozlov V.K. IMMUNE STATE OF THE CHILDREN WITH BRONCHIAL ASTHMA FROM THE AMUR RIVER AND YAKUTIA REGIONS. Medical Immunology (Russia). 2013;15(4):383-387. (In Russ.) https://doi.org/10.15789/1563-0625-2013-4-383-387
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