AUTOANTIBODIES TO GLUTAMIC ACID DECARBOXYLASE AS A PATHOGENETIC MARKER OF TYPE I DIABETES MELLITUS
https://doi.org/10.15789/1563-0625-2011-2-3-257-260
Abstract
Abstract. A new method of enzyme-linked immunosorbent assay (in solid-phase ELISA format) has been developed to determine concentrations of autoantibodies to glutamic acid decarboxylase, as well as an evidencebased methodology is proposed for its medical implications, as a quantitative pathogenetic predictive marker of autoimmune diagnostics in type 1 diabetes mellitus. This technique could be implied for serial production of diagnostic reagent kits, aimed for detection of autoantibodies to glutamic acid decarboxylase by means of ELISA approach. (Med. Immunol., 2011, vol. 13, N 2-3, pp 257-260)
About the Authors
N. V. Piven
ГНУ «Институт биоорганической химии НАН Беларуси», г. Минск
Russian Federation
Russian Federation
L. N. Lukhverchyk
ГНУ «Институт биоорганической химии НАН Беларуси», г. Минск
Russian Federation
Russian Federation
A. I. Burakovsky
ГНУ «Институт биоорганической химии НАН Беларуси», г. Минск
Russian Federation
Russian Federation
N. V. Polegenkaya
ГНУ «Институт биоорганической химии НАН Беларуси», г. Минск
Russian Federation
Russian Federation
M. V. Karpovich
ГНУ «Институт биоорганической химии НАН Беларуси», г. Минск
Russian Federation
Russian Federation
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Review
For citations:
Piven N.V., Lukhverchyk L.N., Burakovsky A.I., Polegenkaya N.V., Karpovich M.V. AUTOANTIBODIES TO GLUTAMIC ACID DECARBOXYLASE AS A PATHOGENETIC MARKER OF TYPE I DIABETES MELLITUS. Medical Immunology (Russia). 2011;13(2-3):257-260. (In Russ.) https://doi.org/10.15789/1563-0625-2011-2-3-257-260
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