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MODES OF INTERACTION BETWEEN SPERMATOZOID ABNORMALITIES AND CYTOKINES IN SEMINAL PLASMA FROM INFERTILE MALES

https://doi.org/10.15789/1563-0625-2008-2-3-203-208

Abstract

Abstract. Spearman rank correlation analysis was applied to assess some interrelations between morphological abnormalities of spermatozoids in males with long-term infertility, and cytokine levels in their seminal plasma. Such statistical analysis has revealed a significant positive correlation between prevalence of morphologically abnormal spermatozoids and the levels of IL-1β, MIP-1β, G-CSF, along with negative relationship with IL-5 and IL-10 contents in seminal fluid. The data are, generally, demonstrating participation of cytokines in regulation of male fertility. (Med. Immunol., 2008, Vol. 10, N 2-3, pp 203-208).

About the Authors

B. I. Aisikovich
Медицинский Центр «Авиценна», г. Новосибирск
Russian Federation


I. V. Aisikovich
Медицинский Центр «Авиценна», г. Новосибирск
Russian Federation


O. Yu. Verba
Медицинский Центр «Авиценна», г. Новосибирск
Russian Federation


V. A. Kozlov
ГУ Научно-исследовательский институт клинической иммунологии СО РАМН, г. Новосибирск
Russian Federation


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Review

For citations:


Aisikovich B.I., Aisikovich I.V., Verba O.Yu., Kozlov V.A. MODES OF INTERACTION BETWEEN SPERMATOZOID ABNORMALITIES AND CYTOKINES IN SEMINAL PLASMA FROM INFERTILE MALES. Medical Immunology (Russia). 2008;10(2-3):203-208. (In Russ.) https://doi.org/10.15789/1563-0625-2008-2-3-203-208

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