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Медицинская иммунология

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РОЛЬ РАЗЛИЧНЫХ СУБПОПУЛЯЦИЙ CD4+Т-ЛИМФОЦИТОВ ПРИ БЕРЕМЕННОСТИ

https://doi.org/10.15789/1563-0625-2016-6-521-536

Полный текст:

Аннотация

Важную роль в формировании иммунологической толерантности при беременности играют Т-лимфоциты. В настоящем обзоре рассматривается характеристика Т-лимфоцитов децидуальной оболочки и плаценты, особенности их миграции и функциональной активности при беременности. В обзоре обсуждается роль субпопуляций Th1-, Th17-, Th2- и Treg-лимфоцитов в формировании плаценты и иммунорегуляции беременности, а также их взаимодействие с клетками децидуальной оболочки и трофобласта.

Об авторах

Д. И. Соколов
ФГБНУ «Научно-исследовательский институт акушерства, гинекологии и репродуктологии им Д.О. Отта» Санкт-Петербург, Россия
Россия

 д.б.н., заведующий лабораторией межклеточных взаимодействий, отдел иммунологии и межклеточных взаимодействий 



О. И. Степанова
ФГБНУ «Научно-исследовательский институт акушерства, гинекологии и репродуктологии им Д.О. Отта» Санкт-Петербург, Россия
Россия

к.б.н., старший научный сотрудник лаборатории межклеточных взаимодействий, отдел иммунологии и межклеточных взаимодействий 



С. А. Сельков
ФГБНУ «Научно-исследовательский институт акушерства, гинекологии и репродуктологии им Д.О. Отта» Санкт-Петербург, Россия
Россия

 д.м.н., профессор, руководитель отдела иммунологии и межклеточных взаимодействий 



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Для цитирования:


Соколов Д.И., Степанова О.И., Сельков С.А. РОЛЬ РАЗЛИЧНЫХ СУБПОПУЛЯЦИЙ CD4+Т-ЛИМФОЦИТОВ ПРИ БЕРЕМЕННОСТИ. Медицинская иммунология. 2016;18(6):521-536. https://doi.org/10.15789/1563-0625-2016-6-521-536

For citation:


Sokolov D.I., Stepanova O.I., Selkov S.I. THE ROLE OF THE DIFFERENT SUBPOPULATIONS OF CD4+Т LYMPHOCYTES DURING PREGNANCY. Medical Immunology (Russia). 2016;18(6):521-536. (In Russ.) https://doi.org/10.15789/1563-0625-2016-6-521-536

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