mimmunМедицинская иммунологияMedical Immunology (Russia)1563-06252313-741XSPb RAACI10.15789/1563-0625-2013-4-313-324mimmun-642Research ArticleОБЗОРЫREVIEWSХРОНИЧЕСКАЯ КРАПИВНИЦА В ДЕТСКОМ ВОЗРАСТЕ. ФОРМЫ ХРОНИЧЕСКОЙ КРАПИВНИЦЫ У ДЕТЕЙ. ДИФФЕРЕНЦИАЛЬНАЯ ДИАГНОСТИКА (ЧАСТЬ II)CHRONIC URTICARIAL IN CHILDHOOD. CLINICAL FEATURES OF CHRONIC URTICARIA IN CHILDREN. DIFFERENTIAL DIAGNOSTICS (PART II)СинельниковаН. А.SinelnikovaN. A.

заочный аспирант кафедры факультетской педиатрии

198097, пр. Стачек, 32, кв. 42. Тел.: 8 (921) 302-28-00. Факс: 8 (812) 542-80-14

PhD candidate, Department of Faculty Pediatrics

198097, Stachek pr., 32, apt 42. Phone: 7 (921) 302-28-00. Fax: 7 (812) 542-80-14

N_Sinelnikova@mail.ruКалининаН. М.KalininaN. M.

д.м.н., профессор

PhD, MD (Medicine), Professor

N_Sinelnikova@mail.ruСавенковаН. Д.SavenkovaN. D.

д.м.н., профессор, кафедра факультетской педиатрии

PhD, MD (Medicine), Professor, Department of Faculty Pediatrics

N_Sinelnikova@mail.ruСанкт-Петербургский государственный педиатрический медицинский университет, Санкт-ПетербургРоссияSt. Petersburg State Pediatric Medical University, St. PetersburgRussian FederationВсероссийский центр экстренной и радиационной медицины МЧС России, Санкт-ПетербургРоссияAll-Russian Center of Extremal and Radiation Medicine, Russian Ministry of Extreme Situations, St. PetersburgRussian Federation201324072014154313324Copyright © Синельникова Н.А., Калинина Н.М., Савенкова Н.Д., 20142014Синельникова Н.А., Калинина Н.М., Савенкова Н.Д.Sinelnikova N.A., Kalinina N.M., Savenkova N.D.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.mimmun.ru/mimmun/article/view/642

Резюме. Структура крапивницы у детей в последнее десятилетие претерпела изменения в связи с открытием аутоиммунной формы, на которую приходится от 30 до 52% от всех случаев хронической идиопатической крапивницы. Физические крапивницы диагностируются в 17-20% случаев и другие формы, в том числе аллергическая, выявляются менее чем в 5%. Разные типы хронической крапивницы имеют свои характерные иммунологические черты и клинические особенности. Продолжается совместная работа экспертной группы европейских аллергологов-иммунологов и дерматологов по уточнению диагностических критериев и подходов к профилактике и терапии этой патологии у детей.

Abstract. Clinical structure of urticaria has been changed over last decade, due to discovery of an autoimmune form of the disease. This clinical form of chronic idiopathic urticaria comprises 30 to 52% of total. Incidence of physical urticaria varies from 17 to 20%, whereas other forms, including allergic urticaria, are diagnosed for < 5% of the patients. Different types of chronic urticaria exhibit their typical immunological features and clinical characteristics. A joint study of European Expert Group for Allergology, Clinical Immunology and Dermatology (EAACI/GA2LEN/EDF/UNEV) is going on. Appropriate recommendations are aimed for improvement of diagnosis and management of children with this disease.

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The authors declare that there are no conflicts of interest present.