mimmunМедицинская иммунологияMedical Immunology (Russia)1563-06252313-741XSPb RAACI10.15789/1563-0625-2013-3-215-226mimmun-618Research ArticleОБЗОРЫREVIEWSМНОГОЛИКАЯ АЛЛЕРГИЯ НА ПЕРСИК: СЕНСИБИЛИЗАЦИЯ К МОЛЕКУЛЯРНЫМ КОМПОНЕНТАМ АЛЛЕРГЕНОВ ИЗ PRUNUS PERSICADIVERSE PEACH ALLERGY: SENSITIZATION TO MOLECULAR COMPONENTS OF ALLERGENS FROM PRUNUS PERSICAМокроносоваМ. А.MokronosovaM. A.

д.м.н., профессор, заведующая лабораторией клинической аллергологии

105064, Малый Казенный пер., 5а. Тел.: 8 (495) 917-08-91. Факс: 8 (495) 917-49-00

PhD, MD (Medicine), Professor, Chief, Laboratory of Clinical Allergology

105064, Malyy Kazennyy lane, 5а. Phone: 7 (495) 917-08-91. Fax: 7 (495) 917-49-00

elen208@yandex.ruКоровкинаЕ. С.KorovkinaE. S.

к.м.н., старший научный сотрудник лаборатории клинической аллергологии

PhD (Medicine), Senior Research Associate, Laboratory of Clinical Allergology

elen208@yandex.ruФедеральное государственное бюджетное учреждение «Научно-исследовательский институт вакцин и сывороток им. И.И. Мечникова» РАМН, МоскваРоссияI.I. Mechnikov’s Research Institute of Vaccines and Sera RAMS, MoscowRussian Federation201324072014153215226Copyright © Мокроносова М.А., Коровкина Е.С., 20142014Мокроносова М.А., Коровкина Е.С.Mokronosova M.A., Korovkina E.S.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.mimmun.ru/mimmun/article/view/618

Резюме. Результаты иммунологических и молекулярно-биологических исследований последних десятилетий позволили четко определить механизмы возникновения и особенности течения аллергических реакций на пищевые продукты растительного происхождения, в том числе и аллергии на плоды Prunus persica – персики и нектарины. В данной статье приводится анализ литературных данных, касающихся аллергических реакций на персик, а также клинических наблюдений за больными с подобной аллергией и результатов компонентной аллергодиагностики ISAC ImmunoCAP, проведенной этим пациентам. Накопленные данные позволяют выделить два принципиально разных типа аллергических реакций на Prunus persica. Это обусловленные сенсибилизацией к аллергену Pru p 3 тяжелые системные реакции и обусловленные сенсибилизацией к Pru p 1 или Pru p 4 локальные реакции, проявляющиеся синдромом оральной аллергии и связанные с сенсибилизацией к пыльцевым аллергенам.

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The authors declare that there are no conflicts of interest present.