mimmunМедицинская иммунологияMedical Immunology (Russia)1563-06252313-741XSPb RAACI10.15789/1563-0625-2011-1-7-16mimmun-428Research ArticleОБЗОРЫREVIEWSЦИТОМЕТРИЧЕСКИЙ АНАЛИЗ СУБПОПУЛЯЦИЙ Т-ХЕЛПЕРОВ (TH1, TH2, TREG, TH17, Т-ХЕЛПЕРЫ АКТИВИРОВАННЫЕ)ANALYSIS OF T HELPER SUBPOPULATIONS (Th1, Th2, Treg, Th17, ACTIVATED T-HELPERS) BY MEANS OF FLOW CYTOMETRYХайдуковС. В.KhaidukovS. V.

117997, Москва, ул. Миклухо-Маклая, 16/10.

khsv@mail.ibch.ruЗурочкаА. В.ZurochkaA. V.khsv@mail.ibch.ruИнститут биоорганической химии им. акад. М.М. Шемякина и Ю.А. Овчинникова РАН, Москва ФГУ Федеральный Научно-Клинический Центр детской гематологии, онкологии и иммунологии РОСЗДРАВА, МоскваРоссияИнститут иммунологии и физиологии УрО РАН, г. ЕкатеринбургРоссия201121072014131716Copyright © Хайдуков С.В., Зурочка А.В., 20142014Хайдуков С.В., Зурочка А.В.Khaidukov S.V., Zurochka A.V.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.mimmun.ru/mimmun/article/view/428

Резюме. В последние годы уделяется огромное внимание различным субпопуляциям Т-лимфоцитов. Особенно интенсивно развивается направление, связанное с изучением Т-хелперов. Данная группа клеток оказалась в значительной степени структурирована на различные клеточные субпопуляции. Выявлен и достаточно изучен целый ряд таких субпопуляций, получивших название Th1, Th2, Treg, Th17, а также активированные Т-хелперы. В настоящее время имеются четкие данные о рецепторах и функциональной значимости различных субпопуляций Т-хелперов. Использование этих данных в лабораторных исследованиях, несомненно, скажется на качестве диагностики нарушений функционирования иммунной системы и адекватности назначаемой иммунотерапии.

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The authors declare that there are no conflicts of interest present.