References

mimmun

Медицинская иммунология

Medical Immunology (Russia)

1563-06252313-741X

SPb RAACI

10.15789/1563-0625-2011-1-17-28

mimmun-411

Research Article

ОБЗОРЫ

REVIEWS

СИНДРОМ ОРАЛЬНОЙ АЛЛЕРГИИ

ORAL ALLERGY SYNDROME

Сергеев

А. В.

Sergeev

A. V.

105064, Москва, Малый Казенный пер., 5а.

avs.allergy@gmail.com

Мокроносова

М. А.

Mokronosova

M. A.

105064, Москва, Малый Казенный пер., 5а.

avs.allergy@gmail.com

Научно-исследовательский институт вакцин и сывороток им. И.И. Мечникова РАМН, МоскваRussian Federation

2011

21072014

1311728

2014

Сергеев А.В., Мокроносова М.А.

Sergeev A.V., Mokronosova M.A.

Данная работа распространяется под лицензией Creative Commons Attribution 4.0.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://www.mimmun.ru/mimmun/article/view/411

Abstract. Oral allergy syndrome (OAS) is defined as a set of clinical manifestations caused by IgE-mediated allergic reactions that occur at oral and pharyngeal mucosae in the patients with pollen sensitization after ingestion of certain fruits, vegetables, nuts and spices. OAS arises from cross-reactivity between specific pollen and food allergens, due to similarity of a configuration and amino acid sequence of allergenic molecules. OAS is considered as class II food allergy, being caused by thermo- and chemolabile allergens, and it is rarely combined with generalized manifestations of food allergy. Prevalence and spectrum of the causal allergens depend on a kind of pollen sensitization. In Moscow region, as well as in Northern Europe, allergic sensitization most commonly occurs to the pollen of leaf trees, whereas OAS is mostly connected with ingestion of fruits from Rosaceae family and nuts. Since last years, a newly developed technique of component-resolved molecular diagnosis (CR diagnostics) allows of more precise detection of OAS-causing allergen molecules. These data are of extreme importance for administration of adequate nutritional therapy and prediction of SIT efficiency. (Med. Immunol., 2011, vol. 13, N 1, pp 17-28)

Поллинозсиндром оральной аллергииCR-диагностика

pollinosisoral allergy syndromeCR-diagnosis

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The authors declare that there are no conflicts of interest present.