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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">mimmun</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинская иммунология</journal-title><trans-title-group xml:lang="en"><trans-title>Medical Immunology (Russia)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1563-0625</issn><issn pub-type="epub">2313-741X</issn><publisher><publisher-name>SPb RAACI</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15789/1563-0625-2012-4-5-429-432</article-id><article-id custom-type="elpub" pub-id-type="custom">mimmun-372</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КРАТКИЕ СООБЩЕНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>SHORT COMMUNICATIONS</subject></subj-group></article-categories><title-group><article-title>ВЛИЯНИЕ ЭСТРИОЛА НА ФУНКЦИОНАЛЬНУЮ АКТИВНОСТЬ МОНОЦИТОВ В СИСТЕМЕ IN VITRO</article-title><trans-title-group xml:lang="en"><trans-title>EFFECT OF ESTRIOL ON THE FUNCTIONAL ACTIVITY OF MONOCYTES IN VITRO</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Долгушин</surname><given-names>И. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Dolgushin</surname><given-names>I. I.</given-names></name></name-alternatives><email xlink:type="simple">tanya_bondarenko@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Смирнова</surname><given-names>Т. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Smirnova</surname><given-names>T. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>454092, г. Челябинск, ул. Воровского, 64. Тел: (963) 089-29-82</p></bio><email xlink:type="simple">tanya_bondarenko@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Савочкина</surname><given-names>А. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Savochkina</surname><given-names>A. Yu.</given-names></name></name-alternatives><email xlink:type="simple">tanya_bondarenko@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шишкова</surname><given-names>Ю. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Shishkova</surname><given-names>Yu. S.</given-names></name></name-alternatives><email xlink:type="simple">tanya_bondarenko@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Прокопьева</surname><given-names>О. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Prokopyeva</surname><given-names>O. B.</given-names></name></name-alternatives><email xlink:type="simple">tanya_bondarenko@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мезенцева</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Mezentseva</surname><given-names>E. A.</given-names></name></name-alternatives><email xlink:type="simple">tanya_bondarenko@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>НИИ Иммунологии ГБОУ ВПО ЧелГМА Минздравсоцразвития России, г. Челябинск</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2012</year></pub-date><pub-date pub-type="epub"><day>20</day><month>07</month><year>2014</year></pub-date><volume>14</volume><issue>4-5</issue><fpage>429</fpage><lpage>432</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Долгушин И.И., Смирнова Т.Г., Савочкина А.Ю., Шишкова Ю.С., Прокопьева О.Б., Мезенцева Е.А., 2014</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="ru">Долгушин И.И., Смирнова Т.Г., Савочкина А.Ю., Шишкова Ю.С., Прокопьева О.Б., Мезенцева Е.А.</copyright-holder><copyright-holder xml:lang="en">Dolgushin I.I., Smirnova T.G., Savochkina A.Y., Shishkova Y.S., Prokopyeva O.B., Mezentseva E.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.mimmun.ru/mimmun/article/view/372">https://www.mimmun.ru/mimmun/article/view/372</self-uri><abstract/><trans-abstract xml:lang="en"><p>Abstract. Employing an in vitro cellular system, we have studied effects of estriol at physiological concentrations corresponding to the 1st, 2nd , and 3rd trimesters of pregnancy upon phagocytic, bactericidal activity of monocytes, and their ability to form extracellular traps. This steroid hormone does not significantly affect phagocytic function of monocytes at concentrations corresponding to the 1st, 2nd , and 3rd trimesters of pregnancy, however, leads to increased formation of extracellular traps and increase of oxygen-dependent bactericidal effects.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>моноцитарные внеклеточные ловушки</kwd><kwd>эстриол</kwd><kwd>фагоцитоз</kwd></kwd-group><kwd-group xml:lang="en"><kwd>monocyte extracellular traps4 estriol</kwd><kwd>phagocytosis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Гадиева Ф.Г. 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