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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">mimmun</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинская иммунология</journal-title><trans-title-group xml:lang="en"><trans-title>Medical Immunology (Russia)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1563-0625</issn><issn pub-type="epub">2313-741X</issn><publisher><publisher-name>SPb RAACI</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15789/1563-0625-2009-6-499-508</article-id><article-id custom-type="elpub" pub-id-type="custom">mimmun-349</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>ДЕЙСТВИЕ МОДУЛЯТОРОВ АКТИВНОСТИ МЕВАЛОНАТНОГО БИОХИМИЧЕСКОГО ПУТИ НА РЕАКТИВНОСТЬ МАКРОФАГОВ ПРИ ЭКСПЕРИМЕНТАЛЬНОМ НЕФРОСКЛЕРОЗЕ</article-title><trans-title-group xml:lang="en"><trans-title>EFFECTS OF MEVALONATE PATHWAY MODULATORS UPON REACTIVITY OF MACROPHAGES IN E XPERIMENTAL NEPHROSCLEROSIS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шварц</surname><given-names>Я. Ш.</given-names></name><name name-style="western" xml:lang="en"><surname>Schwarz</surname><given-names>Ya. Sh.</given-names></name></name-alternatives><bio xml:lang="ru"><p>630004, ул. Урицкого, 35, кв. 7. Тел.: (3892) 229-51-57. Факс: (4967) 229-51-57</p></bio><email xlink:type="simple">yshschwartz@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Белогородцев</surname><given-names>С. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Belogorodtsev</surname><given-names>S. N.</given-names></name></name-alternatives><email xlink:type="simple">yshschwartz@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Филимонов</surname><given-names>П. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Filimonov</surname><given-names>P. N.</given-names></name></name-alternatives><email xlink:type="simple">yshschwartz@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Селедцова</surname><given-names>Г. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Seledtsova</surname><given-names>G. V.</given-names></name></name-alternatives><email xlink:type="simple">yshschwartz@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>ГУ НИИ терапии СО РАМН, г. Новосибирск</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-2"><institution>ГУ НИИ клинической иммунологии СО РАМН, г. Новосибирск</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-3"><institution>ФГУ Новосибирский НИИ туберкулеза МЗСР РФ, г. Новосибирск</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2009</year></pub-date><pub-date pub-type="epub"><day>20</day><month>07</month><year>2014</year></pub-date><volume>11</volume><issue>6</issue><fpage>499</fpage><lpage>508</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шварц Я.Ш., Белогородцев С.Н., Филимонов П.Н., Селедцова Г.В., 2014</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="ru">Шварц Я.Ш., Белогородцев С.Н., Филимонов П.Н., Селедцова Г.В.</copyright-holder><copyright-holder xml:lang="en">Schwarz Y.S., Belogorodtsev S.N., Filimonov P.N., Seledtsova G.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.mimmun.ru/mimmun/article/view/349">https://www.mimmun.ru/mimmun/article/view/349</self-uri><abstract/><trans-abstract xml:lang="en"/><kwd-group xml:lang="ru"><kwd>нефросклероз</kwd><kwd>макрофаги</kwd><kwd>холестерин</kwd><kwd>мевалонат</kwd><kwd>оксид азота</kwd></kwd-group><kwd-group xml:lang="en"><kwd>nephrosclerosis</kwd><kwd>macrophages</kwd><kwd>cholesterol</kwd><kwd>mevalonic acid</kwd><kwd>nitric oxide</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Маянский Д.Н., Шварц Я.Ш., Цырендоржиев Д.Д., Кутина С.Н. 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