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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">mimmun</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинская иммунология</journal-title><trans-title-group xml:lang="en"><trans-title>Medical Immunology (Russia)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1563-0625</issn><issn pub-type="epub">2313-741X</issn><publisher><publisher-name>SPb RAACI</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15789/1563-0625-2012-1-2-95-102</article-id><article-id custom-type="elpub" pub-id-type="custom">mimmun-302</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>ОПСОНИЗИРУЮЩИЕ СВОЙСТВА КОММЕРЧЕСКОГО АНТИСТАФИЛОКОККОВОГО ИММУНОГЛОБУЛИНА</article-title><trans-title-group xml:lang="en"><trans-title>OPSONIZING PROPERTIES OF A COMMERCIAL ANTISTAPHYLOCOCCAL IMMUNOGLOBULIN</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Слободчикова</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Slobodchikova</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>614081, г. Пермь, ул. Голева, 13. Тел.: (342) 280-74-42, 280-83-34. Факс: (342) 280-92-11</p></bio><email xlink:type="simple">ecolimmlab@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шмагель</surname><given-names>К. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Schmagel</surname><given-names>K. V.</given-names></name></name-alternatives><bio xml:lang="ru"/><email xlink:type="simple">ecolimmlab@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Институт экологии и генетики микроорганизмов УрО РАН, г. Пермь</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-2"><institution>Институт экологии и генетики микроорганизмов УрО РАН, г. Пермь&#13;
&#13;
Пермская государственная медицинская академия им. акад. Е.А. Вагнера, г. Пермь</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2012</year></pub-date><pub-date pub-type="epub"><day>19</day><month>07</month><year>2014</year></pub-date><volume>14</volume><issue>1-2</issue><fpage>95</fpage><lpage>102</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Слободчикова С.В., Шмагель К.В., 2014</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="ru">Слободчикова С.В., Шмагель К.В.</copyright-holder><copyright-holder xml:lang="en">Slobodchikova S.V., Schmagel K.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.mimmun.ru/mimmun/article/view/302">https://www.mimmun.ru/mimmun/article/view/302</self-uri><abstract/><trans-abstract xml:lang="en"/><kwd-group xml:lang="ru"><kwd>антистафилококковый иммуноглобулин</kwd><kwd>нормальный иммуноглобулин</kwd><kwd>S. aureus</kwd><kwd>опсонизация</kwd><kwd>фагоцитоз</kwd></kwd-group><kwd-group xml:lang="en"><kwd>antistaphylococcal immunoglobulin</kwd><kwd>normal immunoglobulin</kwd><kwd>S. aureus</kwd><kwd>opsonization</kwd><kwd>phagocytosis</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Программа Президиума РАН «Фундаментальные науки – медицине». № проекта: 09-П-4-1015</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Выгодчиков Г.В. Стафилококковые инфекции (микробиология, иммунология и эпидемиология). – M.: Медгиз, 1963. – 272 c.</mixed-citation><mixed-citation xml:lang="en">Выгодчиков Г.В. Стафилококковые инфекции (микробиология, иммунология и эпидемиология). – M.: Медгиз, 1963. – 272 c.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Карницкая Н.В., Левина М.Н., Лукатос Е.А. Нормальный γ-глобулин человека как носитель специфических антистафилококковых антител // Препараты нормальных и специфических иммуноглобулинов человека. Сборник научных трудов Московского НИИ эпидемиологии и микробиологии. – 1975. – Т. XVIII. – C. 102-106.</mixed-citation><mixed-citation xml:lang="en">Карницкая Н.В., Левина М.Н., Лукатос Е.А. Нормальный γ-глобулин человека как носитель специфических антистафилококковых антител // Препараты нормальных и специфических иммуноглобулинов человека. Сборник научных трудов Московского НИИ эпидемиологии и микробиологии. – 1975. – Т. XVIII. – C. 102-106.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Кленин В.И., Щеголев С.Ю., Лаврушин В.И. Характеристические функции светорассеяния дисперсных систем. – Изд-во Саратовского университета. – 1977. – 177 с.</mixed-citation><mixed-citation xml:lang="en">Кленин В.И., Щеголев С.Ю., Лаврушин В.И. Характеристические функции светорассеяния дисперсных систем. – Изд-во Саратовского университета. – 1977. – 177 с.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Королевская Л.Б., Шмагель К.В. Спектротурбидиметрическое определение размера иммунных агрегатов сывороток крови, образованных в полиэтиленгликоле // Иммунология. – 2010. – № 2. – С. 108-111.</mixed-citation><mixed-citation xml:lang="en">Королевская Л.Б., Шмагель К.В. Спектротурбидиметрическое определение размера иммунных агрегатов сывороток крови, образованных в полиэтиленгликоле // Иммунология. – 2010. – № 2. – С. 108-111.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Пинегин Б.В., Ярилин А.А., Симонова А.В., Климова С.В, Мазуров Д.В, Дамбаева С.В., Бахус Г.О. Оценка поглотительной активности фагоцитов периферической крови человека // Применение проточной цитометрии для оценки функциональной активности иммунной системы человека. Пособие для врачей лаборантов. – М., 2001. – С. 31-35.</mixed-citation><mixed-citation xml:lang="en">Пинегин Б.В., Ярилин А.А., Симонова А.В., Климова С.В, Мазуров Д.В, Дамбаева С.В., Бахус Г.О. Оценка поглотительной активности фагоцитов периферической крови человека // Применение проточной цитометрии для оценки функциональной активности иммунной системы человека. Пособие для врачей лаборантов. – М., 2001. – С. 31-35.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Слободчикова С.В., Шмагель К.В., Раев М.Б., Бахметьев Б.А. Влияние человеческого трофобластического β1-гликопротеина на стимулированную люминолзависимую хемилюминесценцию лейкоцитов // Российский иммунологический журнал. – 2009. – № 3 (12). – С. 338-342.</mixed-citation><mixed-citation xml:lang="en">Слободчикова С.В., Шмагель К.В., Раев М.Б., Бахметьев Б.А. Влияние человеческого трофобластического β1-гликопротеина на стимулированную люминолзависимую хемилюминесценцию лейкоцитов // Российский иммунологический журнал. – 2009. – № 3 (12). – С. 338-342.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Aydogan M., Eifan A.O., Gocmen I., Ozdemir C., Bahceciler N.N., Barlan I.B. Clinical and Immunologic Features of Pediatric Patients With Common Variable Immunodeficiency and Respiratory Complications // J. Investig. Allergol. Clin. Immunol. – 2008. – Vol. 18, N 4. – P. 260-265.</mixed-citation><mixed-citation xml:lang="en">Aydogan M., Eifan A.O., Gocmen I., Ozdemir C., Bahceciler N.N., Barlan I.B. Clinical and Immunologic Features of Pediatric Patients With Common Variable Immunodeficiency and Respiratory Complications // J. Investig. Allergol. Clin. Immunol. – 2008. – Vol. 18, N 4. – P. 260-265.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Champion J.A., Walker A., Mitragotri S. Role of Particle Size in Phagocytosis of Polymeric Microspheres // Pharm. Res. – 2008. – Vol. 25, N 8. – P. 1815-1821.</mixed-citation><mixed-citation xml:lang="en">Champion J.A., Walker A., Mitragotri S. Role of Particle Size in Phagocytosis of Polymeric Microspheres // Pharm. Res. – 2008. – Vol. 25, N 8. – P. 1815-1821.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">DeLeo F.R., Diep B.A., Otto M. Host defense and pathogenesis in Staphylococcus aureus infections // Infect. Dis. Clin. North. Am. – 2009. – Vol. 23, N 1. – P. 17-34.</mixed-citation><mixed-citation xml:lang="en">DeLeo F.R., Diep B.A., Otto M. Host defense and pathogenesis in Staphylococcus aureus infections // Infect. Dis. Clin. North. Am. – 2009. – Vol. 23, N 1. – P. 17-34.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Dryla A., Prustomersky S., Gelbmann D., Hanner M., Bettinger E., Kocsis B., Kustos T., Henics T., Meinke A., Nagy E. Comparison of Antibody Repertoires against Staphylococcus aureus in Healthy Individuals and in Acutely Infected Patients // Clin. Diagn. Lab. Immunol. – 2005. – Vol. 12, N 3. – P. 387-398.</mixed-citation><mixed-citation xml:lang="en">Dryla A., Prustomersky S., Gelbmann D., Hanner M., Bettinger E., Kocsis B., Kustos T., Henics T., Meinke A., Nagy E. Comparison of Antibody Repertoires against Staphylococcus aureus in Healthy Individuals and in Acutely Infected Patients // Clin. Diagn. Lab. Immunol. – 2005. – Vol. 12, N 3. – P. 387-398.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Durandy A., Kaveri S.V., Kuijpers T.W., Basta M., Miescher S., Ravetch J.V., Rieben R. Intravenous immunoglobulins – understanding properties and mechanisms // Clinical and Experimental Immunology. – 2009. – Vol. 158. – P. 2-13.</mixed-citation><mixed-citation xml:lang="en">Durandy A., Kaveri S.V., Kuijpers T.W., Basta M., Miescher S., Ravetch J.V., Rieben R. Intravenous immunoglobulins – understanding properties and mechanisms // Clinical and Experimental Immunology. – 2009. – Vol. 158. – P. 2-13.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Garcıa-Garcıa E., Rosales C. Signal transduction during Fc receptor-mediated phagocytosis // J. Leukoc. Biol. – 2002. – Vol. 72. – P. 1092-1108.</mixed-citation><mixed-citation xml:lang="en">Garcıa-Garcıa E., Rosales C. Signal transduction during Fc receptor-mediated phagocytosis // J. Leukoc. Biol. – 2002. – Vol. 72. – P. 1092-1108.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Ishikawa Y., Muramatsu N., Ohshima H., Kondo T. Effect of particle size on phagocytosis of latex particles by guinea-pig polymorphonuclear leucocytes // J. Biomater. Sci. Polym. Ed. – 1991. – N 2 (1). – P. 53-60.</mixed-citation><mixed-citation xml:lang="en">Ishikawa Y., Muramatsu N., Ohshima H., Kondo T. Effect of particle size on phagocytosis of latex particles by guinea-pig polymorphonuclear leucocytes // J. Biomater. Sci. Polym. Ed. – 1991. – N 2 (1). – P. 53-60.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Iwatsuki K., Yamasaki O., Morizane S., Oono T. Staphylococcal cutaneous infections: Invasion, evasion and aggression // Journal of Dermatological Science. – 2006. – Vol. 42. – P. 203-214.</mixed-citation><mixed-citation xml:lang="en">Iwatsuki K., Yamasaki O., Morizane S., Oono T. Staphylococcal cutaneous infections: Invasion, evasion and aggression // Journal of Dermatological Science. – 2006. – Vol. 42. – P. 203-214.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Kelly J. Immunotherapy against antibioticresistant bacteria: the Russian experience with an antistaphylococcal hyperimmune plasma and immunoglobulin // Microbes and Infection. – 2000. – N 2. – P. 1383-1392.</mixed-citation><mixed-citation xml:lang="en">Kelly J. Immunotherapy against antibioticresistant bacteria: the Russian experience with an antistaphylococcal hyperimmune plasma and immunoglobulin // Microbes and Infection. – 2000. – N 2. – P. 1383-1392.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Kluytmans J., Belkum van A., Verbrugh H. Nasal carriage of Staphylococcus aureus: epidemiology, underlying mechanisms, and associatedrisks // Clin. Microbiol. Rev. – 1997. – Vol. 10, N 3. – P. 505-520.</mixed-citation><mixed-citation xml:lang="en">Kluytmans J., Belkum van A., Verbrugh H. Nasal carriage of Staphylococcus aureus: epidemiology, underlying mechanisms, and associatedrisks // Clin. Microbiol. Rev. – 1997. – Vol. 10, N 3. – P. 505-520.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Lekstrom-Himes J.A., Gallin J.I. Immunodeficiency diseases caused by defects in phagocytes // The New England Journal of Medicine. – 2000. – Vol. 343, N 23. – P. 1703-1714.</mixed-citation><mixed-citation xml:lang="en">Lekstrom-Himes J.A., Gallin J.I. Immunodeficiency diseases caused by defects in phagocytes // The New England Journal of Medicine. – 2000. – Vol. 343, N 23. – P. 1703-1714.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Middleton J.R. Staphylococcus aureus antigens and challenges in vaccine development // Expert Rev. Vaccines. – 2008. – Vol. 7, N 6. – P. 805-815.</mixed-citation><mixed-citation xml:lang="en">Middleton J.R. Staphylococcus aureus antigens and challenges in vaccine development // Expert Rev. Vaccines. – 2008. – Vol. 7, N 6. – P. 805-815.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Molne L., Verdrengh M., Tarkowski A. Role of neutrophil leukocytes in cutaneous infection caused by Staphylococcus aureus // Infection and immunity. – 2000. – Vol. 68, N 11. – P. 6162-6167.</mixed-citation><mixed-citation xml:lang="en">Molne L., Verdrengh M., Tarkowski A. Role of neutrophil leukocytes in cutaneous infection caused by Staphylococcus aureus // Infection and immunity. – 2000. – Vol. 68, N 11. – P. 6162-6167.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Pease L.F., Elliott J.T., Tsai D.H., Zachariah M.R., Tarlov M.J. Determination of Protein Aggregation With Differential Mobility Analysis: Application to IgG Antibody // Biotechnol. Bioeng. – 2008. – Vol. 101. – P. 1214-1222.</mixed-citation><mixed-citation xml:lang="en">Pease L.F., Elliott J.T., Tsai D.H., Zachariah M.R., Tarlov M.J. Determination of Protein Aggregation With Differential Mobility Analysis: Application to IgG Antibody // Biotechnol. Bioeng. – 2008. – Vol. 101. – P. 1214-1222.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Pross H., Eidinger D. In vitro Stuides of ‘Antigenic Competition’ II. Reconstitution of the immune defect and the relationship between antigeninduced supression and non-specific enhancement // lmmunology. – 1973. – Vol. 25. – P. 269.</mixed-citation><mixed-citation xml:lang="en">Pross H., Eidinger D. In vitro Stuides of ‘Antigenic Competition’ II. Reconstitution of the immune defect and the relationship between antigeninduced supression and non-specific enhancement // lmmunology. – 1973. – Vol. 25. – P. 269.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Quie P.G., Cates K.L. Clinical conditions associated with defective polymorphonuclear leukocyte chemotaxis // Am. J. Pathol. – 1977. – Vol. 88, N 3. – P. 711-725.</mixed-citation><mixed-citation xml:lang="en">Quie P.G., Cates K.L. Clinical conditions associated with defective polymorphonuclear leukocyte chemotaxis // Am. J. Pathol. – 1977. – Vol. 88, N 3. – P. 711-725.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Singh B.R., Chandra M., Agrawal R.K., Nagrajan B. Antigenic competition among different ‘O’ antigens of Salmonella enterica subspecies enterica serovars during hyperimmunization in pony mares // Indian. J. Exp. Biol. – 2006. – Vol. 44, N 12. – P. 1022-1025.</mixed-citation><mixed-citation xml:lang="en">Singh B.R., Chandra M., Agrawal R.K., Nagrajan B. Antigenic competition among different ‘O’ antigens of Salmonella enterica subspecies enterica serovars during hyperimmunization in pony mares // Indian. J. Exp. Biol. – 2006. – Vol. 44, N 12. – P. 1022-1025.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Yamada S. Chemiluminescence response of human phagocytes against IgG-opsonized staphylococci with and without protein A activities // Microbiol. Immunol. – 1990. – Vol. 34, N 3. – P. 221-229.</mixed-citation><mixed-citation xml:lang="en">Yamada S. Chemiluminescence response of human phagocytes against IgG-opsonized staphylococci with and without protein A activities // Microbiol. Immunol. – 1990. – Vol. 34, N 3. – P. 221-229.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
