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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">mimmun</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинская иммунология</journal-title><trans-title-group xml:lang="en"><trans-title>Medical Immunology (Russia)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1563-0625</issn><issn pub-type="epub">2313-741X</issn><publisher><publisher-name>SPb RAACI</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15789/1563-0625-2014-1-7-26</article-id><article-id custom-type="elpub" pub-id-type="custom">mimmun-18</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>ОСНОВНЫЕ ПОВЕРХНОСТНЫЕ МАРКЕРЫ ФУНКЦИОНАЛЬНОЙ АКТИВНОСТИ Т-ЛИМФОЦИТОВ</article-title><trans-title-group xml:lang="en"><trans-title>BASIC SURFACE MARKERS OF FUNCTIONAL ACTIVITY T-LYMPHOCYTES</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Литвинова</surname><given-names>Л. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Litvinova</surname><given-names>L. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор, заведующаялабораторией иммунологиии клеточных биотехнологийИнновационного парка</p></bio><bio xml:lang="en"><p>PhD, MD (Medicine), Professor, Head of Laboratoryof Immunology and Cell Biotechnology, Innovative Park, ImmanuelKant Baltic Federal University</p></bio><email xlink:type="simple">larisalitvinova@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гуцол</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Gutsol</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>аспирант, младший научный сотрудниклаборатории иммунологии и клеточных биотехнологийИнновационного парка БФУ им. И. Канта</p></bio><bio xml:lang="en"><p>Postgraduate Student, Research Associate of Laboratoryof Immunology and Cell Biotechnology, Innovative Park, ImmanuelKant Baltic Federal University</p></bio><email xlink:type="simple">larisalitvinova@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сохоневич</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sokhonevich</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>аспирант, младший научный сотрудниклаборатории иммунологии и клеточных биотехнологийИнновационного парка БФУ им. И. Канта</p></bio><bio xml:lang="en"><p>Postgraduate Student , Research Associate ofLaboratory of Immunology and Cell Biotechnology, Innovative Park,Immanuel Kant Baltic Federal University</p></bio><email xlink:type="simple">larisalitvinova@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кофанова</surname><given-names>К. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kofanova</surname><given-names>K. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>аспирант, лаборатория иммунологиии клеточных биотехнологий Инновационного парка БФУим. И. Канта</p></bio><bio xml:lang="en"><p>Postgraduate Student, Laboratory of Immunology andCell Biotechnology, Innovative Park, Immanuel Kant Baltic FederalUniversity, Kaliningrad</p></bio><email xlink:type="simple">larisalitvinova@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хазиахматова</surname><given-names>О. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Khaziakhmatova</surname><given-names>O. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>биолог, аспирант, лабораторияиммунологии и клеточных биотехнологий Инновационного паркаБФУ им. И. Канта</p></bio><bio xml:lang="en"><p>Postgraduate Student, Biologist, Laboratory ofImmunology and Cell Biotechnology, Innovative Park, Immanuel KantBaltic Federal University</p></bio><email xlink:type="simple">larisalitvinova@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шуплецова</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shupletsova</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>научный сотрудник лаборатории иммунологиии клеточных биотехнологий Инновационного парка БФУим. И. Канта</p></bio><bio xml:lang="en"><p>Research Associate of Laboratory of Immunologyand Cell Biotechnology, Innovative Park, Immanuel Kant BalticFederal University</p></bio><email xlink:type="simple">larisalitvinova@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кайгородова</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kaigorodova</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>старший научный сотрудник лабораториииммунологии и клеточных биотехнологий Инновационного паркаБФУ им. И. Канта</p></bio><bio xml:lang="en"><p>Senior Research Associate of Laboratory ofImmunology and Cell Biotechnology, Innovative Park, Immanuel KantBaltic Federal University</p></bio><email xlink:type="simple">larisalitvinova@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гончаров</surname><given-names>А. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Goncharov</surname><given-names>A. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., доцент, кафедра молекулярнойфизиологии и биофизики химико-биологического институтаБФУ им. И. Канта</p></bio><bio xml:lang="en"><p>PhD (Medicine), Associate Professor, Department ofMolecular Physiology and Biophysics, Institute of Chemical Biology,Immanuel Kant Baltic Federal University</p></bio><email xlink:type="simple">larisalitvinova@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Балтийский федеральный университет имени&#13;
И. Канта, г. Калининград</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Immanuel Kant Baltic Federal University, Kaliningrad</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>05</day><month>07</month><year>2014</year></pub-date><volume>16</volume><issue>1</issue><fpage>7</fpage><lpage>26</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Литвинова Л.С., Гуцол А.А., Сохоневич Н.А., Кофанова К.А., Хазиахматова О.Г., Шуплецова В.В., Кайгородова Е.В., Гончаров А.Г., 2014</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="ru">Литвинова Л.С., Гуцол А.А., Сохоневич Н.А., Кофанова К.А., Хазиахматова О.Г., Шуплецова В.В., Кайгородова Е.В., Гончаров А.Г.</copyright-holder><copyright-holder xml:lang="en">Litvinova L.S., Gutsol A.A., Sokhonevich N.A., Kofanova K.A., Khaziakhmatova O.G., Shupletsova V.V., Kaigorodova E.V., Goncharov A.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.mimmun.ru/mimmun/article/view/18">https://www.mimmun.ru/mimmun/article/view/18</self-uri><abstract><p>В настоящем обзоре предпринята попытка систематизировать существующие представления о наиболее значимых поверхностных антигенах иммунокомпетентных клеток и оценить их роль в процессах клеточного гомеостаза и формировании патологии.</p></abstract><trans-abstract xml:lang="en"/><kwd-group xml:lang="ru"><kwd>Т-лимфоциты</kwd><kwd>активация</kwd><kwd>пролиферация</kwd><kwd>апоптоз</kwd></kwd-group><kwd-group xml:lang="en"><kwd>T lymphocytes</kwd><kwd>activation</kwd><kwd>proliferation</kwd><kwd>apoptosis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Антонеева И.И., Петров С.Б. 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